Anti-inflammatory and biologic drugs for atopic dermatitis: a therapeutic approach in children and adolescents.
Janus Kinase
atopic dermatitis
biologics
children
dupilumab
lebrikizumab
small molecules
tralokinumab
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2023
2023
Historique:
received:
30
04
2023
accepted:
27
07
2023
medline:
1
9
2023
pubmed:
1
9
2023
entrez:
1
9
2023
Statut:
epublish
Résumé
Atopic dermatitis (AD) is a chronic inflammatory disease with a heterogeneous pathogenesis correlated with dysregulation of the immune system and a prevalence of the T2-mediated immune pathway. Recent understanding of the pathogenesis of AD has allowed the development of new drugs targeting different mechanisms and cytokines that have changed the treatment approach. The aim of this review is to update knowledge on the standard of care and recent advancements in the control of skin inflammation. In light of recent guidelines, we report on the clinical efficacy of novel treatments, with special attention to situations where biologics and small molecules are involved.
Identifiants
pubmed: 37654660
doi: 10.3389/fmed.2023.1214963
pmc: PMC10466416
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1214963Informations de copyright
Copyright © 2023 Caffarelli, Giannetti, Giannì and Ricci.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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