Scalable Electrochemical Decarboxylative Olefination Driven by Alternating Polarity.
Decarboxylation
Electrochemistry
Olefination
Reaction Mechanisms
Synthetic Methods
Journal
Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543
Informations de publication
Date de publication:
16 Oct 2023
16 Oct 2023
Historique:
received:
28
06
2023
pubmed:
1
9
2023
medline:
1
9
2023
entrez:
1
9
2023
Statut:
ppublish
Résumé
A mild, scalable (kg) metal-free electrochemical decarboxylation of alkyl carboxylic acids to olefins is disclosed. Numerous applications are presented wherein this transformation can simplify alkene synthesis and provide alternative synthetic access to valuable olefins from simple carboxylic acid feedstocks. This robust method relies on alternating polarity to maintain the quality of the electrode surface and local pH, providing a deeper understanding of the Hofer-Moest process with unprecedented chemoselectivity.
Identifiants
pubmed: 37656907
doi: 10.1002/anie.202309157
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202309157Subventions
Organisme : National Science Foundation
ID : CHE-2002158
Organisme : Horizon 2020 Framework Programme
ID : H2020-MSCA-IF-2020-GF-101027337- CatToSat
Informations de copyright
© 2023 The Authors. Angewandte Chemie International Edition published by Wiley-VCH GmbH.
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