Confirmed cases of COVID-19 after vaccination against COVID in health personnel in Bogotá, Colombia.


Journal

Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899

Informations de publication

Date de publication:
22 09 2023
Historique:
received: 22 12 2021
revised: 31 07 2023
accepted: 31 07 2023
medline: 25 9 2023
pubmed: 4 9 2023
entrez: 4 9 2023
Statut: ppublish

Résumé

The present study aims to estimate the frequency of COVID 19 infections in vaccinated health personnel at a Los CObos Medical Center in Bogotá, Colombia. The percentage of people positive to the PCR test and their clinical characteristics were analyzed. We performed a cross-sectional study. The primary study variable was the COVID vaccination registry. We analyzed sex, age, signs, and symptoms. Multivariable logistic regression was applied to assess changes over time and to identify variables associated with vaccination in target groups. A cohort of 999 people working at Los Cobos Medical Center and followed from March to August 2021. The average age of this cohort was 37.0 years (devest = 10.5 years), 67.7 % were women. Two hundred eleven physicians, 287 nurses, 305 assistants, and 196 clerks follows. In addition, 8.4 % to be PCR positive after vaccination. The average age was 36.0 (devest = 23.4 years), 59 women and 25 men. Of these, 15 were administrative, 14 were doctors, 29 nurses, and 26 nursing assistants. The vaccination status found that 21.4 % do not vaccinates, 7.1 % were partially vaccinated, and 71.4 % with a complete schedule. When questioned about symptoms in these patients, 4.0 % were symptomatic, and 5.9 % were asymptomatic. A recent epidemiological study involving 12,364 health workers with a mean age of 38 years quantifies the protection in six months from the vaccine. The presence of antibodies was associated with 83 % protection against active SARS-CoV-2 infection (PCR positivity during the study period), which confirms the existence of protective Immunity at levels comparable to those obtained by the approved vaccines; our study found effectiveness of 92.6 %. Higher than that found in this study, possibly explained by the characteristics of the individuals included.

Identifiants

pubmed: 37661532
pii: S0264-410X(23)00924-6
doi: 10.1016/j.vaccine.2023.07.078
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6072-6076

Informations de copyright

Copyright © 2023. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Alexandra Porras-Ramírez (A)

Grupo de Medicina comunitaria y salud colectiva, Universidad El Bosque, Bogotá, Colombia; Los Cobos Medical Center, Bogotá, Colombia. Electronic address: aporrasr@loscobosmc.com.

Rafael Sánchez-París (R)

Grupo de Medicina comunitaria y salud colectiva, Universidad El Bosque, Bogotá, Colombia.

Walter López-Devia (W)

Los Cobos Medical Center, Bogotá, Colombia.

Zuly Moreno-Perilla (Z)

Los Cobos Medical Center, Bogotá, Colombia.

Roberto Jurado-Zambrano (R)

Los Cobos Medical Center, Bogotá, Colombia.

Carlos Luna-Jaspe Caina (C)

Los Cobos Medical Center, Bogotá, Colombia.

Carlos Sefair (C)

Los Cobos Medical Center, Bogotá, Colombia.

Nicolás Ramos (N)

Los Cobos Medical Center, Bogotá, Colombia.

Miguel Otero-Cadena (M)

Los Cobos Medical Center, Bogotá, Colombia.

Rocío Lievano (R)

Los Cobos Medical Center, Bogotá, Colombia.

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