A suppressor screen
BIOLOGICAL SCIENCES
C. elegans
Genetics
crossover
meiosis
suppressor screen
synaptonemal complex
Journal
bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
22 Aug 2023
22 Aug 2023
Historique:
pubmed:
4
9
2023
medline:
4
9
2023
entrez:
4
9
2023
Statut:
epublish
Résumé
Successful chromosome segregation into gametes depends on tightly-regulated interactions between the parental chromosomes. During meiosis, chromosomes are aligned end-to-end by an interface called the synaptonemal complex, which also regulates exchanges between them. However, despite the functional and ultrastructural conservation of this essential interface, how protein-protein interactions within the synaptonemal complex regulate chromosomal interactions remains poorly understood. Here we describe a novel interaction interface in the
Identifiants
pubmed: 37662357
doi: 10.1101/2023.08.21.554166
pmc: PMC10473659
pii:
doi:
Types de publication
Preprint
Langues
eng
Subventions
Organisme : NCI NIH HHS
ID : P30 CA042014
Pays : United States
Organisme : NIH HHS
ID : P40 OD010440
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM128804
Pays : United States
Organisme : NICHD NIH HHS
ID : T32 HD007491
Pays : United States
Déclaration de conflit d'intérêts
Competing Interest Statement: The authors declare no competing interests.