The Association of Children's Blood Lead Levels and Prevalence of Stunting in Tin Mining Area in Indonesia.
Indonesia
blood lead levels
children
stunting
tin mining
Journal
Annals of global health
ISSN: 2214-9996
Titre abrégé: Ann Glob Health
Pays: United States
ID NLM: 101620864
Informations de publication
Date de publication:
2023
2023
Historique:
received:
17
03
2023
accepted:
22
07
2023
medline:
5
9
2023
pubmed:
4
9
2023
entrez:
4
9
2023
Statut:
epublish
Résumé
Metal mining and smelting activities are regarded as major sources of heavy metals such as lead, mercury, arsenic and cadmium in the environment and in humans living at the surrounding area. Among others, lead can enter and accumulate in the human body and be very influential in children's growth and development. This study aims to assess the association between children's blood lead levels and stunting in a mining area in Indonesia. A cross-sectional design was implemented by involving 193 children living in surrounding tin mining in Bangka Island, Indonesia. Venous blood was drawn and blood lead level was measured by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Stunting status was measured by anthropometry standing height and converted to sexand age-specific Z-scores based on World Health Organization (WHO) growth reference. Children's dietary intake was assessed using 24-hour dietary recall method. Statistics of chi-square test and multiple logistic regression were performed for the analyses. The geometric mean of Blood Lead Levels (BLLs) was 5.5 µg/dl (± 2.6 µg/dl; 95% CI: 5.1-5.9). The interquartile range of BLLs and height for age Z-score (HAZ) were 3.0 μg/dl and -1.5, respectively. The data revealed that 23.3% of children were stunted (HAZ < -2). The multiple logistic regression models suggest that elevated BLLs were an independent predictor of the stunting. The odds stunted blood lead concentration was elevated about 10times higher [adjusted odd ratio (AOR) = 9.75 (95% Confidence interval (CI): 3.1-30.7); p < 0.001] in comparison to the odds of normal BLLs.The BLLs of children at ages two to nine years were found associated with stunting after controlling of the mother›s education, residence and the intake of energy, protein, zinc, vitamin A, calcium and phosphorus. The study suggested that living in surrounding tin mining was dangerous for children›s health and their development.
Sections du résumé
Background
Metal mining and smelting activities are regarded as major sources of heavy metals such as lead, mercury, arsenic and cadmium in the environment and in humans living at the surrounding area. Among others, lead can enter and accumulate in the human body and be very influential in children's growth and development.
Objective
This study aims to assess the association between children's blood lead levels and stunting in a mining area in Indonesia.
Methods
A cross-sectional design was implemented by involving 193 children living in surrounding tin mining in Bangka Island, Indonesia. Venous blood was drawn and blood lead level was measured by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Stunting status was measured by anthropometry standing height and converted to sexand age-specific Z-scores based on World Health Organization (WHO) growth reference. Children's dietary intake was assessed using 24-hour dietary recall method. Statistics of chi-square test and multiple logistic regression were performed for the analyses.
Findings
The geometric mean of Blood Lead Levels (BLLs) was 5.5 µg/dl (± 2.6 µg/dl; 95% CI: 5.1-5.9). The interquartile range of BLLs and height for age Z-score (HAZ) were 3.0 μg/dl and -1.5, respectively. The data revealed that 23.3% of children were stunted (HAZ < -2). The multiple logistic regression models suggest that elevated BLLs were an independent predictor of the stunting. The odds stunted blood lead concentration was elevated about 10times higher [adjusted odd ratio (AOR) = 9.75 (95% Confidence interval (CI): 3.1-30.7); p < 0.001] in comparison to the odds of normal BLLs.The BLLs of children at ages two to nine years were found associated with stunting after controlling of the mother›s education, residence and the intake of energy, protein, zinc, vitamin A, calcium and phosphorus.
Conclusion
The study suggested that living in surrounding tin mining was dangerous for children›s health and their development.
Identifiants
pubmed: 37663225
doi: 10.5334/aogh.4119
pmc: PMC10473164
doi:
Substances chimiques
Lead
2P299V784P
Tin
7440-31-5
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
55Informations de copyright
Copyright: © 2023 The Author(s).
Déclaration de conflit d'intérêts
The authors have no competing interests to declare.
Références
Am J Hum Biol. 2009 Mar-Apr;21(2):180-7
pubmed: 18991336
Glob Health Action. 2014 Feb 13;7:22888
pubmed: 24560254
J Pediatr. 2012 Jun;160(6):1044-9
pubmed: 22284921
Environ Health Perspect. 2000 Mar;108 Suppl 1:23-8
pubmed: 10698721
Indian J Occup Environ Med. 2010 Aug;14(2):58-62
pubmed: 21120083
Biomed Res Int. 2017;2017:4934198
pubmed: 28466011
Rural Remote Health. 2022 Mar;22(1):7082
pubmed: 35306826
J Health Popul Nutr. 2012 Dec;30(4):404-9
pubmed: 23304906
Rev Environ Health. 2020 Mar 26;35(1):41-48
pubmed: 32134738
Int J Environ Res Public Health. 2019 Apr 10;16(7):
pubmed: 30974753
Rev Environ Health. 2016 Mar;31(1):13-6
pubmed: 26812760
Community Eye Health. 2013;26(84):61-3
pubmed: 24782578
Environ Health. 2015 Dec 30;14:95
pubmed: 26715556
Environ Health. 2016 Nov 4;15(1):103
pubmed: 27809911
PLoS One. 2018 May 24;13(5):e0197856
pubmed: 29795643
PLoS One. 2020 May 29;15(5):e0233615
pubmed: 32470055
Matern Child Nutr. 2018 Oct;14(4):e12617
pubmed: 29770565