Novel insights into genetic characteristics of

GES hospital sewage integron plasmid toxin-antitoxin system

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2023
Historique:
received: 20 04 2023
accepted: 01 08 2023
medline: 4 9 2023
pubmed: 4 9 2023
entrez: 4 9 2023
Statut: epublish

Résumé

The prevalence of Guiana extended-spectrum (GES)-type carbapenemase producers is increasing worldwide, and hospital water environments are considered as potential reservoirs. However, the genetic features underlying this resistance are not yet fully understood. This study aimed to characterize Carbapenemase producers were screened using carbapenemase-selective agar and polymerase chain reaction. Whole-genome sequencing analyzes were performed on the carbapenemase-producing isolates. Eleven gram-negative bacteria (four The findings on the plasmids and the novel genetic content from a single wastewater sample extend our understanding regarding the diversity of resistance and the associated spread of

Identifiants

pubmed: 37664110
doi: 10.3389/fmicb.2023.1209195
pmc: PMC10469963
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1209195

Informations de copyright

Copyright © 2023 Ota, Prah, Mahazu, Gu, Nukui, Koike and Saito.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Yusuke Ota (Y)

Department of Molecular Microbiology and Immunology, Tokyo Medical and Dental University, Tokyo, Japan.

Isaac Prah (I)

Department of Molecular Microbiology and Immunology, Tokyo Medical and Dental University, Tokyo, Japan.

Samiratu Mahazu (S)

Department of Molecular Microbiology and Immunology, Tokyo Medical and Dental University, Tokyo, Japan.
Department of Parasitology and Tropical Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

Yoshiaki Gu (Y)

Department of Infectious Diseases, Tokyo Medical and Dental University, Tokyo, Japan.

Yoko Nukui (Y)

Department of Infection Control and Laboratory Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Ryuji Koike (R)

Clinical Research Center, Tokyo Medical and Dental University Hospital, Tokyo, Japan.

Ryoichi Saito (R)

Department of Molecular Microbiology and Immunology, Tokyo Medical and Dental University, Tokyo, Japan.

Classifications MeSH