Plant flavonoid inhibition of SARS-CoV-2 main protease and viral replication.
Biochemistry
Biological sciences
Cell biology
Chemistry
Natural product chemistry
Natural sciences
Pharmacology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
15 Sep 2023
15 Sep 2023
Historique:
received:
11
05
2023
revised:
15
06
2023
accepted:
08
08
2023
medline:
4
9
2023
pubmed:
4
9
2023
entrez:
4
9
2023
Statut:
epublish
Résumé
Plant-based flavonoids have been evaluated as inhibitors of β-coronavirus replication and as therapies for COVID-19 on the basis of their safety profile and widespread availability. The SARS-CoV-2 main protease (Mpro) has been implicated as a target for flavonoids
Identifiants
pubmed: 37664626
doi: 10.1016/j.isci.2023.107602
pii: S2589-0042(23)01679-6
pmc: PMC10470319
doi:
Types de publication
Journal Article
Langues
eng
Pagination
107602Informations de copyright
© 2023 The Authors.
Déclaration de conflit d'intérêts
RF and LL have a patent pending entitled, “Compounds and Methods for Treating Viral Infections”. RF is on the Scientific Advisory Board of NytroPonix and is a founder and consultant at PlateletDiagnostics, LLC.
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