Caffeine and neonatal acute kidney injury.

Infant, Newborn Humans Caffeine / adverse effects Infant, Premature Central Nervous System Stimulants / adverse effects Acute Kidney Injury / chemically induced Motivation
Acute kidney injury Caffeine Molecular mechanism Neonatal

Journal

Pediatric nephrology (Berlin, Germany)
ISSN: 1432-198X
Titre abrégé: Pediatr Nephrol
Pays: Germany
ID NLM: 8708728

Informations de publication

Date de publication:
May 2024
Historique:
received: 24 04 2023
accepted: 02 08 2023
revised: 02 08 2023
medline: 18 3 2024
pubmed: 4 9 2023
entrez: 4 9 2023
Statut: ppublish

Résumé

Acute kidney injury is one of the most threatening diseases in neonates, with complex pathogenesis and limited treatment options. Caffeine is a commonly used central nervous system stimulant for treating apnea in preterm infants. There is compelling evidence that caffeine may have potential benefits for preventing neonatal acute kidney injury, but comprehensive reports are lacking in this area. Hence, this review aims to provide a summary of clinical data on the potential benefits of caffeine in improving neonatal acute kidney injury. Additionally, it delves into the molecular mechanisms underlying caffeine's effects on acute kidney injury, with a focus on various aspects such as oxidative stress, adenosine receptors, mitochondrial dysfunction, endoplasmic reticulum stress, inflammasome, autophagy, p53, and gut microbiota. The ultimate goal of this review is to provide information for healthcare professionals regarding the link between caffeine and neonatal acute kidney injury and to identify gaps in our current understanding.

Identifiants

DOI: 10.1007/s00467-023-06122-6 PMID: 37665410
pubmed: 37665410
doi: 10.1007/s00467-023-06122-6
pii: 10.1007/s00467-023-06122-6
doi:

Substances chimiques

Caffeine 3G6A5W338E
Central Nervous System Stimulants 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1355-1367

Subventions

Organisme : National Natural Science Foundation of China
ID : 81571480
Organisme : Sichuan Science and Technology Department Major Science and Technology Special Project
ID : 22ZDYF1470
Organisme : Luzhou Municipal People's Government-Southwest Medical University Science and Technology Strategic Cooperation Project
ID : 2020LZXNYDJ03

Informations de copyright

© 2023. The Author(s), under exclusive licence to International Pediatric Nephrology Association.

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Auteurs

Kun Yang (K)

Division of Neonatology, Department of Pediatrics, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Department of Perinatology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Sichuan Clinical Research Center for Birth Defects, Luzhou, 646000, China.
ORCID: 0000-0002-6252-2782

Jinjing Liu (J)

Division of Neonatology, Department of Pediatrics, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Department of Perinatology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Sichuan Clinical Research Center for Birth Defects, Luzhou, 646000, China.

Ting He (T)

Division of Neonatology, Department of Pediatrics, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Department of Perinatology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China.
Sichuan Clinical Research Center for Birth Defects, Luzhou, 646000, China.

Wenbin Dong (W)

Division of Neonatology, Department of Pediatrics, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China. dongwenbin2000@163.com.
Department of Perinatology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China. dongwenbin2000@163.com.
Sichuan Clinical Research Center for Birth Defects, Luzhou, 646000, China. dongwenbin2000@163.com.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Nouveau-né › Caffeine and neonatal acute kidney injury.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Caffeine and neonatal acute kidney injury.
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Purines › Purinones › Xanthines › Caféine › Caffeine and neonatal acute kidney injury.
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Nouveau-né › Prématuré › Caffeine and neonatal acute kidney injury.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Stimulants du système nerveux central › Caffeine and neonatal acute kidney injury.
questionsmedicales.fr › Maladies urogénitales › Maladies urologiques › Maladies du rein › Insuffisance rénale › Atteinte rénale aigüe › Caffeine and neonatal acute kidney injury.
questionsmedicales.fr › Comportement et mécanismes comportementaux › Personnalité › Intelligence › Intelligence émotionnelle › Motivation › Caffeine and neonatal acute kidney injury.