Robot-assisted PSMA-radioguided Surgery to Assess Surgical Margins and Nodal Metastases in Prostate Cancer Patients: Report on Three Cases Using an Intraoperative PET-CT Specimen Imager.
Journal
Urology
ISSN: 1527-9995
Titre abrégé: Urology
Pays: United States
ID NLM: 0366151
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
received:
17
05
2023
revised:
11
08
2023
accepted:
15
08
2023
medline:
11
12
2023
pubmed:
6
9
2023
entrez:
5
9
2023
Statut:
ppublish
Résumé
The aim of this feasibility study was to test the intraoperative use of this brand-new specimen PET/CT to guide robot-assisted radical prostatectomy and pelvic lymph node dissection. Three cases of robot-assisted radical prostatectomy and pelvic lymph node dissection were performed with intraoperative use of the specimen imager. Surgeries were performed with Da Vinci Xi robot. An intravenous injection of The average nodal yield was 17.3 (5.8 SD) nodes per patient. Specimen PET/CT images showed a focal uptake in a metastatic node (TBR 13.6), and no uptake or diffuse, faint uptake in negative nodes (TBR range: 1-5.3). The specimen imager provided intraoperative PET/CT images that clearly showed negative surgical margins in two patients, whereas the results were uncertain in a locally advanced case. The intraoperative use of the specimen PET/CT imager is safe and feasible and could improve the evaluation of prostate surgical margins and lymph node status.
Identifiants
pubmed: 37669707
pii: S0090-4295(23)00730-6
doi: 10.1016/j.urology.2023.08.013
pii:
doi:
Substances chimiques
Gallium Radioisotopes
0
Types de publication
Video-Audio Media
Langues
eng
Sous-ensembles de citation
IM
Pagination
e257-e261Informations de copyright
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