Pulmonary artery wedge pressure and left ventricular end-diastolic pressure during exercise in patients with dyspnoea.


Journal

ERJ open research
ISSN: 2312-0541
Titre abrégé: ERJ Open Res
Pays: England
ID NLM: 101671641

Informations de publication

Date de publication:
Jul 2023
Historique:
received: 27 12 2022
accepted: 29 01 2023
medline: 6 9 2023
pubmed: 6 9 2023
entrez: 6 9 2023
Statut: epublish

Résumé

Pulmonary artery wedge pressure (PAWP) during exercise, as a surrogate for left ventricular (LV) end-diastolic pressure (EDP), is used to diagnose heart failure with preserved ejection fraction (HFpEF). However, LVEDP is the gold standard to assess LV filling, end-diastolic PAWP (PAWP 46 individuals underwent simultaneous right and left heart catheterisation, at rest and during exercise, to confirm/exclude HFpEF. We evaluated: linear regression between LVEDP and PAWP, Bland-Altman graphs, and the rate of concordance of dichotomised LVEDP and PAWP ≥ or < diagnostic thresholds for HFpEF. At peak exercise, PAWP During exercise, PAWP is accurate but not precise for the estimation of LVEDP. Despite a good rate of concordance, these two measures might occasionally disagree.

Sections du résumé

Background UNASSIGNED
Pulmonary artery wedge pressure (PAWP) during exercise, as a surrogate for left ventricular (LV) end-diastolic pressure (EDP), is used to diagnose heart failure with preserved ejection fraction (HFpEF). However, LVEDP is the gold standard to assess LV filling, end-diastolic PAWP (PAWP
Methods UNASSIGNED
46 individuals underwent simultaneous right and left heart catheterisation, at rest and during exercise, to confirm/exclude HFpEF. We evaluated: linear regression between LVEDP and PAWP, Bland-Altman graphs, and the rate of concordance of dichotomised LVEDP and PAWP ≥ or < diagnostic thresholds for HFpEF.
Results UNASSIGNED
At peak exercise, PAWP
Conclusions UNASSIGNED
During exercise, PAWP is accurate but not precise for the estimation of LVEDP. Despite a good rate of concordance, these two measures might occasionally disagree.

Identifiants

pubmed: 37670852
doi: 10.1183/23120541.00750-2022
pii: 00750-2022
pmc: PMC10475984
pii:
doi:

Types de publication

Journal Article

Langues

eng

Informations de copyright

Copyright ©The authors 2023.

Déclaration de conflit d'intérêts

Conflict of interest: None declared.

Références

Eur Respir J. 2017 Nov 22;50(5):
pubmed: 29167297
Eur Heart J. 2022 May 21;43(20):1941-1951
pubmed: 35139159
Circulation. 2019 Jul 30;140(5):353-365
pubmed: 31132875
PLoS One. 2014 Jan 31;9(1):e87304
pubmed: 24498069
Catheter Cardiovasc Interv. 2020 Apr 1;95(5):1059-1061
pubmed: 31194281
Eur Heart J. 2020 Mar 21;41(12):1286-1297
pubmed: 31435675
Eur Heart J. 2011 Mar;32(6):670-9
pubmed: 21138935
Circ Heart Fail. 2017 Sep;10(9):
pubmed: 28912264
Eur Respir J. 2019 Jan 24;53(1):
pubmed: 30545974
Eur Heart J. 2022 Oct 11;43(38):3618-3731
pubmed: 36017548
Circ Heart Fail. 2010 Sep;3(5):588-95
pubmed: 20543134
Chest. 2009 Jul;136(1):37-43
pubmed: 19255293
Circulation. 2018 Aug 28;138(9):861-870
pubmed: 29792299
Eur J Heart Fail. 2023 Jan;25(1):26-29
pubmed: 36519686
Eur J Heart Fail. 2021 Oct;23(10):1648-1658
pubmed: 34053158
Eur J Heart Fail. 2017 Nov;19(11):1483-1490
pubmed: 28948687
Circ Heart Fail. 2021 May;14(5):e007555
pubmed: 33951935
JAMA Cardiol. 2018 Jun 1;3(6):453-454
pubmed: 29590308
Eur Heart J Cardiovasc Imaging. 2015 Mar;16(3):233-70
pubmed: 25712077
Eur J Heart Fail. 2021 Oct;23(10):1659-1661
pubmed: 34231304
J Heart Lung Transplant. 2014 Feb;33(2):157-62
pubmed: 24268673
ESC Heart Fail. 2022 Oct;9(5):3079-3091
pubmed: 35748109
Am Heart J. 2012 Apr;163(4):589-94
pubmed: 22520524
Eur Heart J. 2019 Oct 21;40(40):3297-3317
pubmed: 31504452
J Card Fail. 2022 Jan;28(1):133-148
pubmed: 34389460

Auteurs

Claudia Baratto (C)

Department of Cardiology, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milan, Italy.

Andrea Faini (A)

Department of Cardiology, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milan, Italy.
Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy.

Gianluca P Gallone (GP)

Department of Cardiology, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milan, Italy.

Céline Dewachter (C)

Department of Cardiology, Cliniques Universitaires de Bruxelles, Hôpital Académique Erasme, Brussels, Belgium.

Giovanni B Perego (GB)

Department of Cardiology, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milan, Italy.

Antoine Bondue (A)

Department of Cardiology, Cliniques Universitaires de Bruxelles, Hôpital Académique Erasme, Brussels, Belgium.

Denisa Muraru (D)

Department of Cardiology, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milan, Italy.
Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.

Michele Senni (M)

Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.
Cardiovascular Department, ASST Papa Giovanni XXIII, Bergamo, Italy.

Luigi P Badano (LP)

Department of Cardiology, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milan, Italy.
Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.

Gianfranco Parati (G)

Department of Cardiology, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milan, Italy.
Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.

Jean-Luc Vachiéry (JL)

Department of Cardiology, Cliniques Universitaires de Bruxelles, Hôpital Académique Erasme, Brussels, Belgium.

Sergio Caravita (S)

Department of Cardiology, Istituto Auxologico Italiano IRCCS, Ospedale San Luca, Milan, Italy.
Department of Management, Information and Production Engineering, University of Bergamo, Dalmine, Italy.

Classifications MeSH