A case of primary mesenteric synovial sarcoma: a challenging presentation.
Intra-abdominal
Mesenteric
Primary
Sarcoma
Synovial
Journal
Surgical case reports
ISSN: 2198-7793
Titre abrégé: Surg Case Rep
Pays: Germany
ID NLM: 101662125
Informations de publication
Date de publication:
06 Sep 2023
06 Sep 2023
Historique:
received:
28
02
2023
accepted:
01
09
2023
medline:
6
9
2023
pubmed:
6
9
2023
entrez:
6
9
2023
Statut:
epublish
Résumé
Synovial sarcoma is an uncommon soft tissue malignancy that mainly occurs near tendon sheath and bone joints. Primary intra-abdominal location is exceedingly rare and characterized by non-specific clinical signs. We report the case of a young female without medical history who presented with acute abdominopelvic pain. Ultrasound echography revealed a right mass measuring 7 cm in greater diameter cystic with solid areas, likely of ovarian origin. A coelioscopy with peritoneal biopsies was performed. Histological examination with immunohistochemistry concluded the diagnosis of GIST. The patient was referred to the surgery department and after laboratory routine analysis and computed tomography, the patient was proposed to surgical management. Per-operative findings revealed a mesenteric mass locally invading the greater omentum and the appendicular wall. Pathological examination with immunochemistry confirmed the diagnosis of mesenteric monophasic synovial sarcoma invading the appendicular wall with positive surgical margins. Chemotherapy was proposed with a good response. Our patient is free from disease 9 months later. We aimed through this case report to discuss mesenteric presentation monophasic SS, mimicking ovarian malignancy, emphasizing clinicopathological features and differential diagnoses.
Sections du résumé
BACKGROUND
BACKGROUND
Synovial sarcoma is an uncommon soft tissue malignancy that mainly occurs near tendon sheath and bone joints. Primary intra-abdominal location is exceedingly rare and characterized by non-specific clinical signs.
CASE PRESENTATION
METHODS
We report the case of a young female without medical history who presented with acute abdominopelvic pain. Ultrasound echography revealed a right mass measuring 7 cm in greater diameter cystic with solid areas, likely of ovarian origin. A coelioscopy with peritoneal biopsies was performed. Histological examination with immunohistochemistry concluded the diagnosis of GIST. The patient was referred to the surgery department and after laboratory routine analysis and computed tomography, the patient was proposed to surgical management. Per-operative findings revealed a mesenteric mass locally invading the greater omentum and the appendicular wall. Pathological examination with immunochemistry confirmed the diagnosis of mesenteric monophasic synovial sarcoma invading the appendicular wall with positive surgical margins. Chemotherapy was proposed with a good response. Our patient is free from disease 9 months later.
CONCLUSIONS
CONCLUSIONS
We aimed through this case report to discuss mesenteric presentation monophasic SS, mimicking ovarian malignancy, emphasizing clinicopathological features and differential diagnoses.
Identifiants
pubmed: 37672124
doi: 10.1186/s40792-023-01744-2
pii: 10.1186/s40792-023-01744-2
pmc: PMC10482802
doi:
Types de publication
Journal Article
Langues
eng
Pagination
158Informations de copyright
© 2023. Japan Surgical Society.
Références
Histopathology. 2004 Sep;45(3):245-53
pubmed: 15330802
Pathology. 2004 Apr;36(2):208-11
pubmed: 15203764
Int J Clin Exp Pathol. 2017 Nov 01;10(11):11143-11146
pubmed: 31966464
Br J Radiol. 1998 Apr;71(844):438-40
pubmed: 9659138
Am J Surg Pathol. 2020 Jul;44(7):922-933
pubmed: 32141887
Intern Med. 2021 Apr 15;60(8):1317-1318
pubmed: 33116019
Mol Clin Oncol. 2017 May;6(5):688-690
pubmed: 28529743
Ann R Coll Surg Engl. 2017 Jul;99(6):e172-e173
pubmed: 28660813
Cancer. 1995 Jun 15;75(12):2862-6
pubmed: 7539716
Case Rep Pathol. 2012;2012:786083
pubmed: 22966471
JSLS. 2010 Jul-Sep;14(3):421-5
pubmed: 21333201
Indian J Surg Oncol. 2018 Dec;9(4):636-639
pubmed: 30538407
Clin Sarcoma Res. 2015 Feb 12;5:7
pubmed: 25699170
J Gastrointest Cancer. 2021 Jun;52(2):809-813
pubmed: 33145622
Korean J Pathol. 2012 Apr;46(2):187-91
pubmed: 23109999
J Cancer Res Ther. 2013 Jan-Mar;9(1):102-4
pubmed: 23575085