A case of pseudogout attack after zoledronic acid treatment in primary hyperparathyroidism.
Hypercalcemia
hyperparathyroidism
pseudogout
zoledronic acid.
Journal
Turkish journal of physical medicine and rehabilitation
ISSN: 2587-1250
Titre abrégé: Turk J Phys Med Rehabil
Pays: Turkey
ID NLM: 101719024
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
07
11
2021
accepted:
07
01
2022
medline:
7
6
2022
pubmed:
7
6
2022
entrez:
7
9
2023
Statut:
epublish
Résumé
Pseudogout (PG) is an inflammatory arthropathy that develops due to the accumulation of calcium pyrophosphate dihydrate crystals in synovial structures. Herein, we present a 59-year-old male patient with PG developed as a result of zoledronic acid (ZA) infusion, which was administered due to primary hyperparathyroidism. The patient with parathyroid adenoma was given ZA since the calcium level did not decrease despite intravenous saline and loop diuretic. One day after ZA administration, the patient had severe pain, fever, and swelling in joints. The radiograph showed chondrocalcinosis. Calcium pyrophosphate deposition were observed in the arthrocentesis fluid under polarized light. The patient's symptoms regressed after anakinra and colchicine treatment. To the best of our knowledge, this is the first case report of a PG attack after ZA treatment for primary hyperparathyroidism. Additionally, there have been few cases of PG after bisphosphonate treatment for osteoporosis in the literature, signifying that more care should be taken when administering bisphosphonate therapy in patients with risk factors.
Identifiants
pubmed: 37674801
doi: 10.5606/tftrd.2023.10135
pmc: PMC10478547
doi:
Types de publication
Case Reports
Langues
eng
Pagination
377-379Informations de copyright
Copyright © 2023, Turkish Society of Physical Medicine and Rehabilitation.
Déclaration de conflit d'intérêts
Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.
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