DNA-dependent protein kinase catalytic subunit binds to the transactivation domain 1 of NF-κB p65.

DNA-Dependent protein kinase catalytic subunit NF-κB p50 NF-κB p65 Nuclear factor-kappa B

Journal

Biochemistry and biophysics reports
ISSN: 2405-5808
Titre abrégé: Biochem Biophys Rep
Pays: Netherlands
ID NLM: 101660999

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 12 05 2023
revised: 27 08 2023
accepted: 28 08 2023
medline: 7 9 2023
pubmed: 7 9 2023
entrez: 7 9 2023
Statut: epublish

Résumé

Nuclear factor-kappa B (NF-κB) is a transcriptional factor that binds to the ∼10-base-pair κB motif on target genes and acts as an inflammatory regulator. Since dysregulation of NF-κB is thought to be related to various diseases, it would be very important to elucidate its post-translational modifications and binding partners in detail and to deeply understand mechanisms of the NF-κB dysregulation. NF-κB p65 is known to interact with the basic transcription factor TFIID subunit hTAF

Identifiants

pubmed: 37674974
doi: 10.1016/j.bbrep.2023.101538
pii: S2405-5808(23)00119-X
pmc: PMC10477060
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101538

Informations de copyright

© 2023 The Authors.

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Yuta Hasegawa (Y)

Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Higashijima 265-1, Akiha-ku, Niigata, Niigata, 956-8603, Japan.

Shinichi Asada (S)

Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Higashijima 265-1, Akiha-ku, Niigata, Niigata, 956-8603, Japan.

Classifications MeSH