Progesterone Hypersensitivity Induced by Exogenous Progesterone Exposure.
angioedema
autoimmune progesterone dermatitis
intramuscular progesterone
progesterone
progesterone hypersensitivity
urticaria
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
accepted:
06
09
2023
medline:
8
9
2023
pubmed:
8
9
2023
entrez:
8
9
2023
Statut:
epublish
Résumé
Progesterone hypersensitivity (PH) is a rare hypersensitivity reaction to either endogenous or exogenous progesterone. There are around 200 reported cases of progesterone hypersensitivity in the medical literature. We present the case of a 31-year-old female who presented with cyclical urticaria and angioedema after exogenous progesterone exposure. Her symptoms would begin a few days before her menstrual cycle began and resolve after menstruation. She only had partial recovery of her symptoms with antihistamines, steroids, montelukast, and omalizumab. She needed treatment with oral contraceptives and had a resolution of symptoms, but subsequently developed a recurrence again. Given the rarity of this condition, the diagnosis is often delayed. This diagnosis should be considered for women of reproductive age who present with cyclic hypersensitivity or allergic symptoms.
Identifiants
pubmed: 37680259
doi: 10.7759/cureus.44776
pmc: PMC10481886
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e44776Informations de copyright
Copyright © 2023, Dhaliwal et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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