Impact of corrosion inhibitors on antibiotic resistance, metal resistance, and microbial communities in drinking water.


Journal

mSphere
ISSN: 2379-5042
Titre abrégé: mSphere
Pays: United States
ID NLM: 101674533

Informations de publication

Date de publication:
24 10 2023
Historique:
medline: 25 10 2023
pubmed: 8 9 2023
entrez: 8 9 2023
Statut: ppublish

Résumé

Corrosion inhibitors, including zinc orthophosphate, sodium orthophosphate, and sodium silicate, are commonly used to prevent the corrosion of drinking water infrastructure. Metals such as zinc are known stressors for antibiotic resistance selection, and phosphates can increase microbial growth in drinking water distribution systems (DWDS). Yet, the influence of corrosion inhibitor type on antimicrobial resistance in DWDS is unknown. Here, we show that sodium silicates can decrease antibiotic resistant bacteria (ARB) and antibiotic-resistance genes (ARGs), while zinc orthophosphate increases ARB and ARGs in source water microbial communities. Based on controlled bench-scale studies, zinc orthophosphate addition significantly increased the abundance of ARB resistant to ciprofloxacin, sulfonamides, trimethoprim, and vancomycin, as well as the genes

Identifiants

pubmed: 37681947
doi: 10.1128/msphere.00307-23
pmc: PMC10597465
doi:

Substances chimiques

sodium silicate IJF18F77L3
Drinking Water 0
Angiotensin Receptor Antagonists 0
Angiotensin-Converting Enzyme Inhibitors 0
Zinc J41CSQ7QDS
Anti-Bacterial Agents 0
Phosphates 0
Sodium 9NEZ333N27

Types de publication

Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0030723

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Lee K Kimbell (LK)

Department of Civil, Construction and Environmental Engineering, Marquette University , Milwaukee, Wisconsin, USA.

Emily Lou LaMartina (EL)

School of Freshwater Sciences, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin, USA.

Stan Kohls (S)

Department of Civil, Construction and Environmental Engineering, Marquette University , Milwaukee, Wisconsin, USA.

Yin Wang (Y)

Department of Civil and Environmental Engineering, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin, USA.

Ryan J Newton (RJ)

School of Freshwater Sciences, University of Wisconsin-Milwaukee , Milwaukee, Wisconsin, USA.

Patrick J McNamara (PJ)

Department of Civil, Construction and Environmental Engineering, Marquette University , Milwaukee, Wisconsin, USA.

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Classifications MeSH