Intravenous Pyogenic Granuloma in the Inguinal Canal Mimicking Lymph Node Metastasis on PSMA PET/CT.


Journal

Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109

Informations de publication

Date de publication:
01 Oct 2023
Historique:
medline: 11 9 2023
pubmed: 8 9 2023
entrez: 8 9 2023
Statut: ppublish

Résumé

We present a 68-year-old man with newly diagnosed high-risk prostate cancer who was referred for PSMA PET/CT after the initial CT showed a contrast-enhanced structure resembling a lymph node in the left inguinal canal. No other findings suggesting metastatic disease were seen on CT or bone scintigraphy. PSMA PET/CT showed moderate PSMA uptake in the inguinal tissue, substantiating an unexpected location of lymph node metastasis. The uncommon location warranted an excision biopsy, and an IV pyogenic granuloma was diagnosed on histological examination, emphasizing the importance of biopsy of unexpected findings.

Identifiants

pubmed: 37682620
doi: 10.1097/RLU.0000000000004796
pii: 00003072-202310000-00037
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e500-e502

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of interest and sources of funding: none declared.

Références

Parker CC, James ND, Brawley CD, et al. Radiotherapy to the prostate for men with metastatic prostate cancer in the UK and Switzerland: long-term results from the STAMPEDE randomised controlled trial. PLoS Med . 2022;19:e1003998.
Hofman MS, Lawrentschuk N, Francis RJ, et al. Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective, randomised, multicentre study. Lancet . 2020;395:1208–1216.
Fendler WP, Calais J, Eiber M, et al. Assessment of 68 Ga-PSMA-11 PET accuracy in localizing recurrent prostate cancer: a prospective single-arm clinical trial. JAMA Oncol . 2019;5:856–863.
Klingenberg S, Fredsøe J, Sørensen KD, et al. Recurrence rate after radical prostatectomy following primary staging of high-risk prostate cancer with (68)Ga-PSMA PET/CT. Acta Oncol . 2022;61:1289–1294.
Zacho HD, Nalliah S, Petersen A, et al. The clinical consequences of routine (68)Ga-PSMA-11 PET/CT in patients with newly diagnosed prostate cancer, ISUP grade 5 and no metastases based on standard imaging—preliminary results. Scand J Urol . 2022;56:353–358.
Chang SS, Reuter VE, Heston WD, et al. Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature. Cancer Res . 1999;59:3192–3198.
Zacho HD, Nielsen JB, Dettmann K, et al. Incidental detection of thyroid metastases from renal cell carcinoma using 68 Ga-PSMA PET/CT to assess prostate cancer recurrence. Clin Nucl Med . 2017;42:221–222.
Artigas C, Otte FX, Lemort M, et al. Vertebral hemangioma mimicking bone metastasis in 68 Ga-PSMA ligand PET/CT. Clin Nucl Med . 2017;42:368–370.
Zacho HD, Pedersen SH, Petersen A, et al. 68 Ga-PSMA PET/CT uptake in the ureter caused by ligand expression in urothelial cancer. Clin Nucl Med . 2020;45:e43–e45.

Auteurs

Sarah Md Skyum (SM)

From the Departments of Nuclear Medicine.

Andrea K Anthonsen (AK)

From the Departments of Nuclear Medicine.

Dmitry Kvon (D)

Urology, Aalborg University Hospital, Aalborg, Denmark.

Helle D Zacho (HD)

From the Departments of Nuclear Medicine.

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Classifications MeSH