Sex Differences in Quality of Life in Patients with Ischemia with No Obstructive Coronary Artery Disease (INOCA): A Patient Self-Report Retrospective Survey from INOCA International.

functional capacity ischemia with no obstructive coronary artery disease (INOCA) ischemic heart disease quality of life sex differences

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
30 Aug 2023
Historique:
received: 03 07 2023
revised: 17 08 2023
accepted: 23 08 2023
medline: 9 9 2023
pubmed: 9 9 2023
entrez: 9 9 2023
Statut: epublish

Résumé

Women with obstructive coronary artery disease (CAD) have a relatively lower quality of life (QoL) compared to men, but our understanding of sex differences in QoL in ischemia with no obstructive coronary artery disease (INOCA) is limited. We conducted a survey of patient members of INOCA International with an assessment of self-reported health measures. Functional capacity was retrospectively estimated using the Duke Activity Status Index (DASI), assessing levels of activities performed before and after INOCA symptom onset. Of the 1579 patient members, the overall survey completion rate was 21%. Women represented 91% of the respondents. Estimated functional capacity, expressed as metabolic equivalents (METs), was higher before compared to after INOCA diagnosis comparably for both women and men. For every one MET decline in functional capacity, there was a significantly greater decline in QoL for men compared with women in physical health (4.0 ± 1.1 vs. 2.9 ± 0.3 days/month,

Identifiants

pubmed: 37685713
pii: jcm12175646
doi: 10.3390/jcm12175646
pmc: PMC10488627
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Arch Intern Med. 2009 May 11;169(9):843-50
pubmed: 19433695
JACC Cardiovasc Interv. 2012 Jun;5(6):646-53
pubmed: 22721660
N Engl J Med. 2000 Feb 17;342(7):454-60
pubmed: 10675425
Int J Cardiol. 2023 Jan 15;371:28-39
pubmed: 36162521
J Am Coll Cardiol. 2015 Oct 27;66(17):1918-33
pubmed: 26493665
Eur Heart J. 2012 Mar;33(6):734-44
pubmed: 21911339
Circulation. 2021 Nov 30;144(22):e368-e454
pubmed: 34709928
N Engl J Med. 2015 Apr 2;372(14):1291-300
pubmed: 25773919
Open Heart. 2019 Feb 2;6(1):e000870
pubmed: 30815267
Eur Heart J. 2006 Jun;27(12):1408-15
pubmed: 16720691
Circulation. 2017 Mar 14;135(11):1075-1092
pubmed: 28289007
Am J Cardiol. 1989 Sep 15;64(10):651-4
pubmed: 2782256
Front Cardiovasc Med. 2021 Oct 14;8:750071
pubmed: 34722680
N Engl J Med. 2005 Aug 4;353(5):468-75
pubmed: 16079370
Eur Heart J. 2021 Nov 21;42(44):4592-4600
pubmed: 34038937
Circulation. 2021 Sep 28;144(13):1008-1023
pubmed: 34058845
Eur Cardiol. 2021 Oct 12;16:e37
pubmed: 34721671
Circ Cardiovasc Qual Outcomes. 2008 Nov;1(2):123-30
pubmed: 20031799
JAMA. 2014 Nov 5;312(17):1754-63
pubmed: 25369489
Neth Heart J. 2021 Oct;29(10):506-517
pubmed: 33954871
J Womens Health Gend Based Med. 2000 Sep;9(7):769-77
pubmed: 11025869
J Am Coll Cardiol. 1994 Feb;23(2):358-63
pubmed: 8294687
Eur Heart J. 2020 Oct 1;41(37):3504-3520
pubmed: 32626906
N Engl J Med. 2010 Mar 11;362(10):886-95
pubmed: 20220183
J Am Coll Cardiol. 1993 Jul;22(1):175-82
pubmed: 8509539
J Am Coll Cardiol. 2018 Dec 11;72(23 Pt A):2841-2855
pubmed: 30266608
Front Cardiovasc Med. 2021 May 03;8:670843
pubmed: 34012986
Circulation. 2017 Feb 7;135(6):521-531
pubmed: 28153989

Auteurs

Sachini Ranasinghe (S)

Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

C Noel Bairey Merz (CNB)

Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Najah Khan (N)

Houston Methodist Hospital, Houston, TX 77030, USA.

Janet Wei (J)

Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Maria George (M)

INOCA International, Glasgow G12 8QQ, UK.

Colin Berry (C)

British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow G12 8QQ, UK.

Alaide Chieffo (A)

IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Department of Medicine, Vita Salute San Raffaele University, 20132 Milan, Italy.

Paolo G Camici (PG)

IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.

Filippo Crea (F)

Department of Cardiology, Catholic University of the Sacred Heart, 00168 Rome, Italy.

Juan Carlos Kaski (JC)

Molecular and Clinical Sciences Research Institute, St. George's University of London, London SW17 0RE, UK.

Mario Marzilli (M)

Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine-Cardiology Division, University of Pisa, 56126 Pisa, Italy.

Martha Gulati (M)

Barbra Streisand Women's Heart Center, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Classifications MeSH