Novel Treatments for Obesity: Implications for Cancer Prevention and Treatment.

anti-obesity agents glucagon-like peptide 1 liraglutide neoplasms obesity weight loss

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
25 Aug 2023
Historique:
received: 08 08 2023
revised: 23 08 2023
accepted: 24 08 2023
medline: 11 9 2023
pubmed: 9 9 2023
entrez: 9 9 2023
Statut: epublish

Résumé

It is now established that obesity is related to a higher incidence of cancer during a lifespan. The effective treatment of obesity opens up new perspectives in the treatment of a relevant modifiable cancer risk factor. The present narrative review summarizes the correlations between weight loss in obesity and cancer. The current knowledge between obesity treatment and cancer was explored, highlighting the greatest potential for its use in the treatment of cancer in the clinical setting. Evidence for the effects of obesity therapy on proliferation, apoptosis, and response to chemotherapy is summarized. While more studies, including large, long-term clinical trials, are needed to adequately evaluate the relationship and durability between anti-obesity treatment and cancer, collaboration between oncologists and obesity treatment experts is increasingly important.

Identifiants

pubmed: 37686769
pii: nu15173737
doi: 10.3390/nu15173737
pmc: PMC10490004
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Carla Micaela Cuttica (CM)

Endocrine Unit, E.O. Ospedali Galliera, 16128 Genoa, Italy.

Irene Maria Briata (IM)

Division of Medical Oncology, E.O. Ospedali Galliera, 16128 Genoa, Italy.

Andrea DeCensi (A)

Division of Medical Oncology, E.O. Ospedali Galliera, 16128 Genoa, Italy.
Wolfson Institute of Population Health, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AD, UK.

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