Neural encoding of instantaneous kinematics of eye-head gaze shifts in monkey superior Colliculus.


Journal

Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179

Informations de publication

Date de publication:
09 09 2023
Historique:
received: 07 02 2023
accepted: 31 08 2023
medline: 11 9 2023
pubmed: 10 9 2023
entrez: 9 9 2023
Statut: epublish

Résumé

The midbrain superior colliculus is a crucial sensorimotor stage for programming and generating saccadic eye-head gaze shifts. Although it is well established that superior colliculus cells encode a neural command that specifies the amplitude and direction of the upcoming gaze-shift vector, there is controversy about the role of the firing-rate dynamics of these neurons during saccades. In our earlier work, we proposed a simple quantitative model that explains how the recruited superior colliculus population may specify the detailed kinematics (trajectories and velocity profiles) of head-restrained saccadic eye movements. We here show that the same principles may apply to a wide range of saccadic eye-head gaze shifts with strongly varying kinematics, despite the substantial nonlinearities and redundancy in programming and execute rapid goal-directed eye-head gaze shifts to peripheral targets. Our findings could provide additional evidence for an important role of the superior colliculus in the optimal control of saccades.

Identifiants

pubmed: 37689726
doi: 10.1038/s42003-023-05305-z
pii: 10.1038/s42003-023-05305-z
pmc: PMC10492853
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

927

Informations de copyright

© 2023. Springer Nature Limited.

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Auteurs

A John van Opstal (AJ)

Section Neurophysics, Donders Centre for Neuroscience, Radboud University, Nijmegen, The Netherlands. john.vanopstal@donders.ru.nl.

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Classifications MeSH