Resuscitation, survival and morbidity of extremely preterm infants in California 2011-2019.


Journal

Journal of perinatology : official journal of the California Perinatal Association
ISSN: 1476-5543
Titre abrégé: J Perinatol
Pays: United States
ID NLM: 8501884

Informations de publication

Date de publication:
09 Sep 2023
Historique:
received: 14 02 2023
accepted: 31 08 2023
revised: 21 08 2023
medline: 10 9 2023
pubmed: 10 9 2023
entrez: 9 9 2023
Statut: aheadofprint

Résumé

To describe changes over time in resuscitation, survival, and morbidity of extremely preterm infants in California. This population-based, retrospective cohort study includes infants born ≤28 weeks. Linked birth certificates and hospital discharge records were used to evaluate active resuscitation, survival, and morbidity across two epochs (2011-2014, 2015-2019). Of liveborn infants, 0.6% were born ≤28 weeks. Active resuscitation increased from 16.9% of 22-week infants to 98.1% of 25-week infants and increased over time in 22-, 23-, and 25-week infants (p-value ≤ 0.01). Among resuscitated infants, survival to discharge increased from 33.2% at 22 weeks to 96.1% at 28 weeks. Survival without major morbidity improved over time for 28-week infants (p-value < 0.01). Among infants ≤28 weeks, resuscitation and survival increased with gestational age and morbidity decreased. Over time, active resuscitation of periviable infants and morbidity-free survival of 28-week infants increased. These trends may inform counseling around extremely preterm birth.

Identifiants

pubmed: 37689808
doi: 10.1038/s41372-023-01774-6
pii: 10.1038/s41372-023-01774-6
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023. The Author(s).

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Auteurs

Brennan V Higgins (BV)

Division of Neonatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA. Brennan.higgins@ucsf.edu.

Rebecca J Baer (RJ)

California Preterm Birth Initiative, University of California, San Francisco, San Francisco, CA, USA.
Department of Pediatrics, University of California San Diego, San Diego, CA, USA.

Martina A Steurer (MA)

Division of Neonatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
California Preterm Birth Initiative, University of California, San Francisco, San Francisco, CA, USA.
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.

Kayla L Karvonen (KL)

Division of Neonatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.

Scott P Oltman (SP)

California Preterm Birth Initiative, University of California, San Francisco, San Francisco, CA, USA.
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.

Laura L Jelliffe-Pawlowski (LL)

California Preterm Birth Initiative, University of California, San Francisco, San Francisco, CA, USA.
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.

Elizabeth E Rogers (EE)

Division of Neonatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.

Classifications MeSH