Endothelial Lipase Variant, T111I, Does Not Alter Inhibition by Angiopoietin-like Proteins.

ANGPTL3 HDL endothelial lipase lipoproteins

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
30 Aug 2023
Historique:
pubmed: 11 9 2023
medline: 11 9 2023
entrez: 11 9 2023
Statut: epublish

Résumé

High levels of HDL-C are correlated with a decreased risk of cardiovascular disease. HDL-C levels are modulated in part by the secreted phospholipase, endothelial lipase (EL), which hydrolyzes the phospholipids of HDL and decreases circulating HDL-C concentrations. A 584C/T polymorphism in

Identifiants

pubmed: 37693454
doi: 10.1101/2023.08.18.553740
pmc: PMC10491130
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIDCD NIH HHS
ID : R01 DC012049
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL130146
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL162698
Pays : United States
Organisme : NIDDK NIH HHS
ID : T32 DK112751
Pays : United States

Auteurs

Kelli L Sylvers-Davie (KL)

Department of Biochemistry and Molecular Biology, University of Iowa, Iowa City, IA 52242.
Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA 52242.

Kaleb C Bierstedt (KC)

Department of Biochemistry and Molecular Biology, University of Iowa, Iowa City, IA 52242.
Department of Biomedical Engineering, University of Iowa, Iowa City, IA 52242.

Michael J Schnieders (MJ)

Department of Biochemistry and Molecular Biology, University of Iowa, Iowa City, IA 52242.
Department of Biomedical Engineering, University of Iowa, Iowa City, IA 52242.

Brandon S J Davies (BSJ)

Department of Biochemistry and Molecular Biology, University of Iowa, Iowa City, IA 52242.
Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA 52242.

Classifications MeSH