Tropomyosin 1 deficiency facilitates cell state transitions to enhance hemogenic endothelial cell specification during hematopoiesis.

Tropomyosin 1 hematopoiesis hemogenic endothelium iPSC

Journal

bioRxiv : the preprint server for biology
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187

Informations de publication

Date de publication:
02 Sep 2023
Historique:
pubmed: 11 9 2023
medline: 11 9 2023
entrez: 11 9 2023
Statut: epublish

Résumé

Tropomyosins coat actin filaments and impact actin-related signaling and cell morphogenesis. Genome-wide association studies have linked

Identifiants

DOI: 10.1101/2023.09.01.555861 PMID: 37693628 PMC: PMC10491315
pubmed: 37693628
doi: 10.1101/2023.09.01.555861
pmc: PMC10491315
pii:
doi:

Types de publication

Preprint

Langues

eng

Auteurs

Madison B Wilken (MB)

Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA.

Gennadiy Fonar (G)

Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA.

Catriana Nations (C)

Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA.
Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

Giulia Pavani (G)

Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA.
Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

Victor Tsao (V)

Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA.
School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA.

James Garifallou (J)

Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA.

Joanna Tober (J)

Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Laura Bennett (L)

Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Jean Ann Maguire (JA)

Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA.

Alyssa Gagne (A)

Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA.

Nkemdilim Okoli (N)

Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA.
School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA.

Paul Gadue (P)

Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA.
Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

Stella T Chou (ST)

Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA.

Nancy A Speck (NA)

Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Deborah L French (DL)

Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA.
Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

Christopher S Thom (CS)

Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA.
Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

Classifications MeSH