Design, synthesis, and molecular docking studies of benzimidazole-1,3,4-triazole hybrids as carbonic anhydrase I and II inhibitors.
1,3,4-triazole
antioxidant
benzimidazole
carbonic anhydrase
molecular docking
Journal
Chemical biology & drug design
ISSN: 1747-0285
Titre abrégé: Chem Biol Drug Des
Pays: England
ID NLM: 101262549
Informations de publication
Date de publication:
12 Sep 2023
12 Sep 2023
Historique:
revised:
25
08
2023
received:
29
04
2023
accepted:
30
08
2023
pubmed:
12
9
2023
medline:
12
9
2023
entrez:
12
9
2023
Statut:
aheadofprint
Résumé
In this study, with an aim to develop novel heterocyclic hybrids as potent enzyme inhibitors, we synthesized a series of 10 novel 2-(4-(4-ethyl-5-(2-(substitutedphenyl)-2-oxo-ethylthio)-4H-1,2,4-triazol-3-yl)-phenyl)-5,6-dimethyl-1H-benzimidazole (5a-5j) derivatives and characterized by
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e14351Informations de copyright
© 2023 John Wiley & Sons Ltd.
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