The prevalence of vitamin D deficiency and associated factors in first-episode psychosis.

cognition psychopathology psychotic disorders schizophrenia vitamin D

Journal

Early intervention in psychiatry
ISSN: 1751-7893
Titre abrégé: Early Interv Psychiatry
Pays: Australia
ID NLM: 101320027

Informations de publication

Date de publication:
12 Sep 2023
Historique:
revised: 29 01 2023
received: 18 08 2022
accepted: 22 08 2023
medline: 13 9 2023
pubmed: 13 9 2023
entrez: 13 9 2023
Statut: aheadofprint

Résumé

Vitamin D deficiency is prevalent in people with established psychotic disorders, but less is known about vitamin D levels in people with first-episode psychosis (FEP). This study aimed to determine the prevalence of vitamin D deficiency in people with FEP and identify the factors associated with vitamin D status. This was a prospective cohort study nested within a randomized controlled trial, which included 37 young people with an FEP with minimal antipsychotic medication exposure. Twenty-four percent of participants were vitamin D deficient, and a further 30% were vitamin D insufficient. There was no association between vitamin D and demographic factors or clinical symptoms (positive, negative, general psychopathology and depressive symptoms) or cognition and functioning. However, vitamin D levels were associated with season of sampling. Considering the longer-term adverse effects associated with vitamin D deficiency, it is warranted to ensure this clinical population receives supplementation if indicated.

Identifiants

pubmed: 37700506
doi: 10.1111/eip.13465
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Morris family Philanthropic foundation
Organisme : University of Melbourne

Informations de copyright

© 2023 The Authors. Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd.

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Auteurs

Jonathan Tsiglopoulos (J)

Orygen, Parkville, Victoria, Australia.
Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.

Nicholas Pearson (N)

Orygen, Parkville, Victoria, Australia.
Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.

Nathan Mifsud (N)

Orygen, Parkville, Victoria, Australia.
Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.

Emily Castagnini (E)

Orygen, Parkville, Victoria, Australia.
Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.

Kelly Allott (K)

Orygen, Parkville, Victoria, Australia.
Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.

Andrew Thompson (A)

Orygen, Parkville, Victoria, Australia.
Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.

Eoin Killackey (E)

Orygen, Parkville, Victoria, Australia.
Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.

Patrick McGorry (P)

Orygen, Parkville, Victoria, Australia.
Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.

Brian O'Donoghue (B)

Orygen, Parkville, Victoria, Australia.
Centre for Youth Mental Health, University of Melbourne, Victoria, Australia.
Department of Psychiatry, University College Dublin, Dublin, Ireland.

Classifications MeSH