Identification and characterization of a novel chromosomal aminoglycoside 3'-
APH(3′)-Id
Kluyvera intermedia
aminoglycoside 3’-O-phosphotransferase
kinetic parameter
resistance gene
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2023
2023
Historique:
received:
17
05
2023
accepted:
17
07
2023
medline:
13
9
2023
pubmed:
13
9
2023
entrez:
13
9
2023
Statut:
epublish
Résumé
Aminoglycosides, as important clinical antimicrobials, are used as second-line drugs for treating multidrug-resistant tuberculosis or combined with β-lactam drugs for treating severe infections such as sepsis. Aminoglycoside-modifying enzyme (AME) is the most important mechanism of aminoglycoside resistance and deserves more attention. The bacterium A novel aminoglycoside 3'- In this work, a novel aminoglycoside 3'-
Sections du résumé
Background
UNASSIGNED
Aminoglycosides, as important clinical antimicrobials, are used as second-line drugs for treating multidrug-resistant tuberculosis or combined with β-lactam drugs for treating severe infections such as sepsis. Aminoglycoside-modifying enzyme (AME) is the most important mechanism of aminoglycoside resistance and deserves more attention.
Methods
UNASSIGNED
The bacterium
Results
UNASSIGNED
A novel aminoglycoside 3'-
Conclusion
UNASSIGNED
In this work, a novel aminoglycoside 3'-
Identifiants
pubmed: 37700861
doi: 10.3389/fmicb.2023.1224464
pmc: PMC10493288
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1224464Informations de copyright
Copyright © 2023 Sha, Lin, Zhang, Zhang, Zhao, Lu, Zhu, Zhang, Li, Zhang, Lin, Li, Bao and Li.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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