Anticholinergic action is rarely a good thing.
anticholinergic
antidepressants
antipsychotics
bladder drugs
cognitive burden
older people
pharmacology
Journal
Therapeutic advances in psychopharmacology
ISSN: 2045-1253
Titre abrégé: Ther Adv Psychopharmacol
Pays: England
ID NLM: 101555693
Informations de publication
Date de publication:
2023
2023
Historique:
received:
23
03
2023
accepted:
11
07
2023
medline:
13
9
2023
pubmed:
13
9
2023
entrez:
13
9
2023
Statut:
epublish
Résumé
The evidence for the risks associated with anticholinergic agents has grown considerably in the last two decades. Not only are they associated with causing peripheral side effects such as dry mouth, blurred vision and constipation, but they can also cause central effects such as cognitive impairment; and more recently, they have consistently been linked with an increased risk of dementia and death in older people. This paper reviews the evidence for the associations of anticholinergic agents and the risk of dementia and increased mortality in dementia.
Identifiants
pubmed: 37701892
doi: 10.1177/20451253231195264
pii: 10.1177_20451253231195264
pmc: PMC10493059
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
20451253231195264Informations de copyright
© The Author(s), 2023.
Déclaration de conflit d'intérêts
The author declares that there is no conflict of interest.
Références
Alzheimers Dement (N Y). 2022 Apr 12;8(1):e12290
pubmed: 35434252
BJU Int. 2020 Jul;126(1):183-190
pubmed: 32167223
J Neurol Neurosurg Psychiatry. 2018 Oct;89(10):1107-1115
pubmed: 30196250
Pharmacol Res Perspect. 2021 May;9(3):e00793
pubmed: 34087056
Int J Chron Obstruct Pulmon Dis. 2007;2(1):33-40
pubmed: 18044064
Arch Gen Psychiatry. 2005 Jul;62(7):792-8
pubmed: 15997021
BMJ. 2018 Apr 25;361:k1315
pubmed: 29695481
Front Neurosci. 2019 Dec 06;13:1309
pubmed: 31866817
Psychogeriatrics. 2018 Jan;18(1):57-63
pubmed: 29372598
J Alzheimers Dis. 2018;65(2):589-596
pubmed: 30056424
Neurosci Biobehav Rev. 2021 Aug;127:296-306
pubmed: 33933505
JAMA Intern Med. 2019 Aug 01;179(8):1084-1093
pubmed: 31233095
Prim Care Companion J Clin Psychiatry. 2004;6(Suppl 2):20-3
pubmed: 16001097
Basic Clin Pharmacol Toxicol. 2019 Jun;124(6):741-748
pubmed: 30511428
Aging Ment Health. 2022 Sep;26(9):1747-1755
pubmed: 34308718
Healthcare (Basel). 2021 May 13;9(5):
pubmed: 34068348
Int J Geriatr Psychiatry. 2020 Sep;35(9):1069-1077
pubmed: 32394521
C R Biol. 2006 May-Jun;329(5-6):419-25
pubmed: 16731499
Aging Ment Health. 2021 Aug;25(8):1475-1482
pubmed: 33073601
Prog Brain Res. 2004;145:59-66
pubmed: 14650906
J Am Med Dir Assoc. 2021 Dec;22(12):2547-2552
pubmed: 34473960
Clin Auton Res. 1991 Mar;1(1):63-72
pubmed: 1668257
J Am Geriatr Soc. 2005 Dec;53(12):2195-201
pubmed: 16398909
PLoS One. 2014 Jan 13;9(1):e83224
pubmed: 24454696
BMJ. 2005 Sep 10;331(7516):529-30
pubmed: 16150746
Drugs Aging. 2012 Apr 1;29(4):259-73
pubmed: 22390261
Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10483-8
pubmed: 10468635
Am J Psychiatry. 2003 Oct;160(10):1823-9
pubmed: 14514497
Aging Med (Milton). 2023 Apr 05;6(2):116-123
pubmed: 37287675
Eur Urol Focus. 2022 Sep;8(5):1433-1440
pubmed: 34742663
Exp Gerontol. 2018 Jun;106:240-245
pubmed: 29452289
Lancet Neurol. 2006 May;5(5):379-80
pubmed: 16632303
Cold Spring Harb Perspect Med. 2011 Sep;1(1):a008862
pubmed: 22229124
Biomed Pharmacother. 2021 Oct;142:112027
pubmed: 34392083
Int Psychogeriatr. 2002 Sep;14(3):307-10
pubmed: 12475091
J Gen Intern Med. 2020 Jul;35(7):2084-2093
pubmed: 32026255
Neurochem Res. 2003 Apr;28(3-4):437-42
pubmed: 12675128
CMAJ. 2013 May 14;185(8):663-70
pubmed: 23359042
BMJ Case Rep. 2009;2009:
pubmed: 21686994
Int J Geriatr Psychiatry. 2017 Jun;32(6):650-656
pubmed: 27280553
Neurourol Urodyn. 2021 Jan;40(1):28-37
pubmed: 33098213
J Am Geriatr Soc. 2011 Aug;59(8):1477-83
pubmed: 21707557
Can Fam Physician. 2015 Feb;61(2):152-8
pubmed: 25676646