Mesenteric Castleman Disease Misdiagnosed as Lymph Node Metastasis of Rectal Cancer on 18 F-FDG PET/CT.


Journal

Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109

Informations de publication

Date de publication:
01 11 2023
Historique:
medline: 24 11 2023
pubmed: 13 9 2023
entrez: 13 9 2023
Statut: ppublish

Résumé

Two years ago, a 64-year-old man underwent an 18 F-FDG PET/CT for staging rectal cancer. Besides the hypermetabolic rectal lesion, the image revealed a mesenteric lymph node with intense activity and multiple lung nodules with slight FDG uptake, which were highly suspected of metastases. After surgery and multiple cycles of chemotherapy, the follow-up 18 F-FDG PET/CT showed remission of all lesions except for the enlarged mesenteric lymph node with higher metabolic activity. Serum CEA remained normal during the follow-up. Postoperative pathology of the mesenteric lymph node confirmed Castleman disease.

Identifiants

pubmed: 37703486
doi: 10.1097/RLU.0000000000004832
pii: 00003072-202311000-00021
doi:

Substances chimiques

Fluorodeoxyglucose F18 0Z5B2CJX4D
Radiopharmaceuticals 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

985-986

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of interest and sources of funding: The authors declared no conflicts of interest. This work was funded by the National High Level Hospital Clinical Research Funding (2022-PUMCH-B-070).

Références

Carbone A, Borok M, Damania B, et al. Castleman disease. Nat Rev Dis Primers . 2021;7:84.
Dispenzieri A, Fajgenbaum DC. Overview of Castleman disease. Blood . 2020;135:1353–1364.
Cronin DMP, Warnke RA. Castleman disease: an update on classification and the spectrum of associated lesions. Adv Anat Pathol . 2009;16:236–246.
Wu D, Lim MS, Jaffe ES. Pathology of Castleman disease. Hematol Oncol Clin North Am . 2018;32:37–52.
Koa B, Borja AJ, Aly M, et al. Emerging role of 18 F-FDG PET/CT in Castleman disease: a review. Insights Imaging . 2021;12:35.
Lee ES, Paeng JC, Park CM, et al. Metabolic characteristics of Castleman disease on 18 F-FDG PET in relation to clinical implication. Clin Nucl Med . 2013;38:339–342.
Wang W, Medeiros LJ. Castleman disease. Surg Pathol Clin . 2019;12:849–863.
Bhogal RH, Wotherspoon A, Khan AK. Mesenteric Castleman's disease mimicking neuroendocrine tumour. Int J Surg Case Rep . 2019;63:56–58.
Wu PS. Mesenteric Castleman's disease: report of a case and literature review. Int J Clin Exp Pathol . 2020;13:2397–2400.

Auteurs

Meixi Liu (M)

From the Departments of Nuclear Medicine.

Jiaolin Zhou (J)

General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China.

Wenjia Zhu (W)

From the Departments of Nuclear Medicine.

Li Huo (L)

From the Departments of Nuclear Medicine.

Wuying Cheng (W)

From the Departments of Nuclear Medicine.

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