On-Chip Fabrication of Colloidal Suprastructures by Assembly and Supramolecular Interlinking of Microgels.

colloidal suprastructures colloidosomes microfluidics microgels pH-responsive supramolecular chemistry

Journal

Small (Weinheim an der Bergstrasse, Germany)
ISSN: 1613-6829
Titre abrégé: Small
Pays: Germany
ID NLM: 101235338

Informations de publication

Date de publication:
13 Sep 2023
Historique:
revised: 25 07 2023
received: 24 04 2023
medline: 14 9 2023
pubmed: 14 9 2023
entrez: 13 9 2023
Statut: aheadofprint

Résumé

In this report, a versatile method is demonstrated to create colloidal suprastructures by assembly and supramolecular interlinking of microgels using droplet-based microfluidics. The behavior of the microgels is systematically investigated to evaluate the influence of their concentration on their distribution between the continuous, the droplet phase, and the interface. At low concentrations, microgels are mainly localized at the water-oil interface whereas an excess of microgels results, following the complete coverage of the water-oil interface, in their distribution in the continuous phase. To stabilize the colloidal suprastructure, on-chip gelation is introduced by adding natural polyphenol tannic acid (TA) in the water phase. TA forms interparticle linking between the poly(N-vinylcaprolactam) (PVCL) microgels by supramolecular interactions. The combination of supramolecular interlinking with the variation of the microgel concentration in microfluidic droplets enables on-chip fabrication of defined colloidal suprastructures with morphologies ranging from colloidosomes to colloidal supraballs. The obtained supracolloidal structures exhibit a pH-responsive behavior with a disintegration at alkaline conditions within a scale of seconds. The destabilization process results from the deprotonation of phenolic groups and destruction of hydrogen bonds with PVCL chains at higher pH.

Identifiants

pubmed: 37705132
doi: 10.1002/smll.202303444
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2303444

Subventions

Organisme : EU and the federal state of North Rhine-Westphalia
ID : EFRE 30 00883 02

Informations de copyright

© 2023 The Authors. Small published by Wiley-VCH GmbH.

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Auteurs

Se-Hyeong Jung (SH)

Functional and Interactive Polymers, Institute of Technical and Macromolecular Chemistry, Worringerweg 2, 52074, Aachen, Germany.
DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.

Fabian Meyer (F)

Functional and Interactive Polymers, Institute of Technical and Macromolecular Chemistry, Worringerweg 2, 52074, Aachen, Germany.
DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.

Sven Hörnig (S)

Functional and Interactive Polymers, Institute of Technical and Macromolecular Chemistry, Worringerweg 2, 52074, Aachen, Germany.
DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.

Michelle Bund (M)

Functional and Interactive Polymers, Institute of Technical and Macromolecular Chemistry, Worringerweg 2, 52074, Aachen, Germany.
DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.

Bernhard Häßel (B)

DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.
Advanced Materials for Biomedicine, Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Worringerweg 2, 52074, Aachen, Germany.

Luis Paulo Busca Guerzoni (LPB)

DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.

Laura De Laporte (L)

DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.
Advanced Materials for Biomedicine, Institute of Technical and Macromolecular Chemistry, RWTH Aachen University, Worringerweg 2, 52074, Aachen, Germany.
Institute for Applied Medical Engineering, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.

Ghazi Ben Messaoud (G)

DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.

Silvia P Centeno (SP)

DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.

Andrij Pich (A)

Functional and Interactive Polymers, Institute of Technical and Macromolecular Chemistry, Worringerweg 2, 52074, Aachen, Germany.
DWI-Leibniz Institute for Interactive Materials e.V., Forckenbeckstr. 50, 52074, Aachen, Germany.
Aachen Maastricht Institute for Biobased Materials (AMIBM), Maastricht University, Brightlands Chemelot Campus, Urmonderbaan 22, RD Geleen, 6167, The Netherlands.

Classifications MeSH