Radioimmunotherapy Targeting B7-H3


Journal

International journal of biological sciences
ISSN: 1449-2288
Titre abrégé: Int J Biol Sci
Pays: Australia
ID NLM: 101235568

Informations de publication

Date de publication:
2023
Historique:
received: 03 07 2023
accepted: 01 08 2023
medline: 15 9 2023
pubmed: 14 9 2023
entrez: 14 9 2023
Statut: epublish

Résumé

Radionuclide drug conjugates (RDCs) with antibodies serve as a novel approach for the treatment of malignant tumors including glioblastoma. However, RDCs require optimal antibodies to work efficiently. Hu4G4, a novel B7-H3-targeting humanized monoclonal IgG1 antibody, is highly specific for the human B7-H3 protein (a marker of tumor cells, including glioblastoma cells). Herein, we established

Identifiants

pubmed: 37705739
doi: 10.7150/ijbs.87763
pii: ijbsv19p4278
pmc: PMC10496502
doi:

Substances chimiques

Iodine-131 0
Antibodies, Monoclonal, Humanized 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4278-4290

Informations de copyright

© The author(s).

Déclaration de conflit d'intérêts

Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

J Mol Recognit. 2005 Jul-Aug;18(4):307-17
pubmed: 15952219
Cancer Immunol Immunother. 2012 Feb;61(2):215-221
pubmed: 22193987
Biomaterials. 2020 Oct;255:120190
pubmed: 32563943
Nat Immunol. 2016 Jul;17(7):797-805
pubmed: 27135602
J Mol Recognit. 2005 Jul-Aug;18(4):273-81
pubmed: 15997470
Mol Ther Oncolytics. 2019 Jul 23;14:279-287
pubmed: 31485480
Annu Rev Immunol. 2013;31:51-72
pubmed: 23157435
Neurologist. 2006 Nov;12(6):279-92
pubmed: 17122724
Nat Rev Cancer. 2012 Dec;12(12):860-75
pubmed: 23151605
Cancer Chemother Pharmacol. 2006 Jan;57(2):145-54
pubmed: 16001167
Nucl Med Mol Imaging. 2018 Aug;52(4):254-265
pubmed: 30100938
Cancer Sci. 2006 Jun;97(6):546-53
pubmed: 16734735
Int J Mol Med. 2018 Dec;42(6):3386-3394
pubmed: 30272348
Clin Cancer Res. 2012 Jul 15;18(14):3834-45
pubmed: 22615450
EMBO J. 2003 Oct 15;22(20):5551-60
pubmed: 14532127
Cancer Res. 2018 Apr 1;78(7):1820-1832
pubmed: 29363548
J Nucl Med. 2004 Aug;45(8):1366-72
pubmed: 15299063
Cell Death Dis. 2016 Feb 18;7:e2097
pubmed: 26890136
Expert Rev Clin Immunol. 2014 Jun;10(6):713-27
pubmed: 24746113
J Immunother Cancer. 2020 Mar;8(1):
pubmed: 32209603
Cell Death Differ. 2017 Sep;24(9):1632-1644
pubmed: 28574504
Tumori. 2018 Jan-Feb;104(1):1-8
pubmed: 28967094
Mol Med. 2014 Apr 01;20:158-63
pubmed: 24618884
Nat Rev Immunol. 2017 Feb;17(2):97-111
pubmed: 27748397
J Clin Oncol. 2017 Jul 20;35(21):2402-2409
pubmed: 28640706
Clin Transl Oncol. 2018 Jul;20(7):928-935
pubmed: 29119458
Cancer Cell. 2013 Nov 11;24(5):589-602
pubmed: 24209604
Neuro Oncol. 2014 Sep;16(9):1159-60
pubmed: 25096192
Nat Med. 2007 Sep;13(9):1050-9
pubmed: 17704786
J Immunother Cancer. 2022 Apr;10(4):
pubmed: 35414591
Nat Rev Immunol. 2018 Apr;18(4):225-242
pubmed: 29151590
Neuropathol Appl Neurobiol. 2018 Feb;44(2):185-206
pubmed: 28767130
Appl Immunohistochem Mol Morphol. 2020 Nov/Dec;28(10):767-775
pubmed: 31714284
Nucl Med Biol. 2005 Jul;32(5):485-93
pubmed: 15982579
Nanomicro Lett. 2020 Nov 22;13(1):29
pubmed: 34138248
Mol Cancer Ther. 2022 Apr 1;21(4):635-646
pubmed: 35149548
Int J Mol Sci. 2019 Feb 22;20(4):
pubmed: 30813267
J Exp Med. 2005 Dec 19;202(12):1691-701
pubmed: 16365148
Anticancer Drugs. 2005 Nov;16(10):1099-108
pubmed: 16222152
Mater Sci Eng C Mater Biol Appl. 2016 Oct 1;67:159-169
pubmed: 27287110
Oncoimmunology. 2018 Sep 5;7(12):e1501137
pubmed: 30524896
Am J Hematol. 2020 Jul;95(7):775-783
pubmed: 32243637
Br J Pharmacol. 2010 Nov;161(6):1219-37
pubmed: 20132208
Lancet Oncol. 2017 Jul;18(7):e414-e423
pubmed: 28677577
MAbs. 2013 Mar-Apr;5(2):297-305
pubmed: 23406896

Auteurs

Meng Zheng (M)

Department of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.
Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou, SZ, China.

Yan Wang (Y)

Department of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.
Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou, SZ, China.
State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, SZ, China.

Fengqing Fu (F)

State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, SZ, China.
Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.

Kaijie Zhang (K)

Department of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.
Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou, SZ, China.

Yanan Wang (Y)

Department of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.
Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou, SZ, China.

Shandong Zhao (S)

Department of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.
Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou, SZ, China.

Qingfeng Liu (Q)

Department of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.
Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou, SZ, China.

Huiwen Mu (H)

Department of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.
Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou, SZ, China.

Xueguang Zhang (X)

State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, SZ, China.
Jiangsu Institute of Clinical Immunology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.
SuZhou Bright Scistar Antibody Biotech co., Ltd, 303-305, Bldg 15, NO.8, Jinfeng Road, Suzhou, SZ, China.

Liyan Miao (L)

Department of Clinical Pharmacology, The First Affiliated Hospital of Soochow University, Suzhou, SZ, China.
Institute for Interdisciplinary Drug Research and Translational Sciences, College of Pharmaceutical Sciences, Soochow University, Suzhou, SZ, China.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH