Contribution and functional connectivity between cerebrum and cerebellum on sub-lexical and lexical-semantic processing of verbs.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2023
2023
Historique:
received:
17
05
2023
accepted:
01
09
2023
medline:
18
9
2023
pubmed:
14
9
2023
entrez:
14
9
2023
Statut:
epublish
Résumé
Language comprehension involves both sub-lexical (e.g., phonological) and lexical-semantic processing. We conducted a task using functional magnetic resonance imaging (fMRI) to compare the processing of verbs in these two domains. Additionally, we examined the representation of concrete-motor and abstract-non-motor concepts by including two semantic categories of verbs: motor and mental. The findings indicate that sub-lexical processing during the reading of pseudo-verbs primarily involves the left dorsal stream of the perisylvian network, while lexical-semantic representation during the reading of verbs predominantly engages the ventral stream. According to the embodied or grounded cognition approach, modality-specific mechanisms (such as sensory-motor systems) and the well-established multimodal left perisylvian network contribute to the semantic representation of both concrete and abstract verbs. Our study identified the visual system as a preferential modality-specific system for abstract-mental verbs, which exhibited functional connectivity with the right crus I/lobule VI of the cerebellum. Taken together, these results confirm the dissociation between sub-lexical and lexical-semantic processing and provide neurobiological evidence of functional coupling between specific visual modality regions and the right cerebellum, forming a network that supports the semantic representation of abstract concepts. Further, the results shed light on the underlying mechanisms of semantic processing and contribute to our understanding of how the brain processes abstract concepts.
Identifiants
pubmed: 37708205
doi: 10.1371/journal.pone.0291558
pii: PONE-D-23-14317
pmc: PMC10501569
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0291558Informations de copyright
Copyright: © 2023 Reyes-Aguilar et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Nat Rev Neurosci. 2008 Nov;9(11):856-69
pubmed: 18843271
J Neurosci. 2012 Aug 15;32(33):11453-60
pubmed: 22895727
Cereb Cortex. 2001 Mar;11(3):267-77
pubmed: 11230098
Brain Lang. 2012 Feb;120(2):187-207
pubmed: 21334056
J Neurophysiol. 2021 Feb 1;125(2):358-384
pubmed: 33427596
Neuroimage. 2006 Oct 1;32(4):1865-78
pubmed: 16766208
Neuroimage. 2004;23 Suppl 1:S208-19
pubmed: 15501092
Psychol Sci. 2010 Jan;21(1):67-74
pubmed: 20424025
J Clin Exp Neuropsychol. 1997 Jun;19(3):331-9
pubmed: 9268808
Curr Biol. 2012 Nov 6;22(21):2059-62
pubmed: 23063434
Cortex. 2018 Mar;100:52-70
pubmed: 29455946
Curr Opin Neurobiol. 2014 Oct;28:136-41
pubmed: 25062474
J Neurosci. 2009 Aug 12;29(32):10171-9
pubmed: 19675251
Cogn Sci. 2007 Sep 10;31(5):733-64
pubmed: 21635316
Cortex. 2020 Mar;124:1-22
pubmed: 31821905
Cereb Cortex. 2008 Jan;18(1):171-7
pubmed: 17507455
Neuropsychologia. 2014 Aug;61:163-74
pubmed: 24956569
Nat Neurosci. 2009 Jun;12(6):718-24
pubmed: 19471271
Brain Lang. 2004 Jun;89(3):617-22
pubmed: 15120553
Brain Lang. 2009 Sep;110(3):149-53
pubmed: 19664816
J Neurophysiol. 2010 Aug;104(2):1177-94
pubmed: 20410363
J Neurosci. 2017 Feb 8;37(6):1604-1613
pubmed: 28069925
Cereb Cortex. 2009 Dec;19(12):2767-96
pubmed: 19329570
Nat Commun. 2020 Jan 16;11(1):321
pubmed: 31949153
Neurol Sci. 2014 Mar;35(3):365-72
pubmed: 23963806
Cognition. 2005 Jan;94(3):B91-100
pubmed: 15617670
Science. 2009 Oct 16;326(5951):372-3
pubmed: 19833945
J Cogn Neurosci. 2011 Jan;23(1):106-18
pubmed: 20044889
Annu Rev Neurosci. 2014;37:347-62
pubmed: 24905595
J Neurosci. 2017 Jun 28;37(26):6231-6241
pubmed: 28546307
Cognition. 2020 Oct;203:104348
pubmed: 32569894
PLoS One. 2018 May 2;13(5):e0196773
pubmed: 29718993
Neuroimage. 2002 Jan;15(1):1-15
pubmed: 11771969
Cereb Cortex. 2017 Jan 1;27(1):294-309
pubmed: 28077514
Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):4957-60
pubmed: 8506341
Hum Brain Mapp. 2011 Jul;32(7):1081-90
pubmed: 20681014
Cortex. 2021 Sep;142:47-61
pubmed: 34182153
Brain. 1998 Apr;121 ( Pt 4):561-79
pubmed: 9577385
Cereb Cortex. 2006 Apr;16(4):475-86
pubmed: 16000652
Front Hum Neurosci. 2014 Dec 23;8:1024
pubmed: 25566039
Neuron. 2004 Jan 22;41(2):301-7
pubmed: 14741110
J Neurosci. 2006 Mar 1;26(9):2424-33
pubmed: 16510720
J Neurosci. 2007 Oct 3;27(40):10659-73
pubmed: 17913900
Neuroimage Clin. 2018 Jan 31;18:215-230
pubmed: 29868446
Physiol Rev. 2011 Oct;91(4):1357-92
pubmed: 22013214
J Neurosci. 2019 Jul 3;39(27):5361-5368
pubmed: 31061085
Front Psychol. 2014 Jul 22;5:772
pubmed: 25101034
Proc Natl Acad Sci U S A. 2008 Nov 18;105(46):18035-40
pubmed: 19004769
Hum Brain Mapp. 2005 Mar;24(3):165-72
pubmed: 15486988
Brain. 2002 May;125(Pt 5):1054-69
pubmed: 11960895
J Cogn Neurosci. 2011 Sep;23(9):2376-86
pubmed: 21126156
PLoS One. 2014 Oct 30;9(10):e111435
pubmed: 25356830
Neuropsychologia. 2004;42(4):512-23
pubmed: 14728923
Annu Rev Psychol. 2008;59:617-45
pubmed: 17705682
Trends Cogn Sci. 2013 May;17(5):241-54
pubmed: 23579055
Neuropsychologia. 1994 Nov;32(11):1325-41
pubmed: 7533275
J Physiol Paris. 2008 Jan-May;102(1-3):59-70
pubmed: 18448316
Front Psychol. 2016 Oct 10;7:1498
pubmed: 27777563
Sci Rep. 2021 Jun 23;11(1):13112
pubmed: 34162936
J Neuropsychol. 2022 Jun;16(2):389-406
pubmed: 34978159
Nat Rev Neurosci. 2007 May;8(5):393-402
pubmed: 17431404
Brain Res Cogn Brain Res. 2005 Dec;25(3):982-93
pubmed: 16310346
Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1644-9
pubmed: 16432232
Brain Lang. 2020 Dec;211:104863
pubmed: 33039774
J Int Neuropsychol Soc. 2016 May;22(5):570-6
pubmed: 27055803
Sci Adv. 2020 Oct 23;6(43):
pubmed: 33097536
J Int Neuropsychol Soc. 2023 Oct;29(8):775-782
pubmed: 36637058
Neuroimage. 2006 Sep;32(3):1413-21
pubmed: 16861011
Cerebellum. 2014 Feb;13(1):151-77
pubmed: 23996631
Nat Methods. 2011 Jun 26;8(8):665-70
pubmed: 21706013
Brain Lang. 2014 May;132:28-42
pubmed: 24727103