Lysosome-Specific Coumarin-Based Fluorescent Bioprobes for

Humans Fluorescent Dyes / chemistry Lysosomes / metabolism Neoplasms / diagnostic imaging Apoptosis Coumarins / therapeutic use

Journal

Bioconjugate chemistry
ISSN: 1520-4812
Titre abrégé: Bioconjug Chem
Pays: United States
ID NLM: 9010319

Informations de publication

Date de publication:
18 10 2023
Historique:
medline: 23 10 2023
pubmed: 14 9 2023
entrez: 14 9 2023
Statut: ppublish

Résumé

About 90% of cancer deaths worldwide are caused by the spread of cancer cells from the primary tumor to distant organs (metastasis). Therefore, there is an urgent need for an early diagnosis and treatment before cancer metastasis occurs. Lysosomes have emerged as attractive targets for cancer diagnosis and treatment because polar defects in lysosomes can induce apoptosis and cell death. Coumarin is a known polar-sensitive dye with good biocompatibility; because of this, we constructed two fluorescent probes of coumarin derivatives with the "D-π-A" structure,

Identifiants

DOI: 10.1021/acs.bioconjchem.3c00361 PMID: 37708446
pubmed: 37708446
doi: 10.1021/acs.bioconjchem.3c00361
doi:

Substances chimiques

Fluorescent Dyes 0
Coumarins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1851-1860

Auteurs

Xian Chen (X)

College of Health Science and Engineering, Hubei University, Wuhan 430062, P. R. China.

Wenjing Wang (W)

College of Health Science and Engineering, Hubei University, Wuhan 430062, P. R. China.

Tangying Ye (T)

College of Health Science and Engineering, Hubei University, Wuhan 430062, P. R. China.

Jialu Kang (J)

College of Health Science and Engineering, Hubei University, Wuhan 430062, P. R. China.

Qianqiu Wang (Q)

National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, Wuhan, Hubei 430068, China.

Wei Yang (W)

College of Health Science and Engineering, Hubei University, Wuhan 430062, P. R. China.

Heshuang Dai (H)

National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, Wuhan, Hubei 430068, China.

Kai Wang (K)

College of Health Science and Engineering, Hubei University, Wuhan 430062, P. R. China.

Jie Pan (J)

College of Health Science and Engineering, Hubei University, Wuhan 430062, P. R. China.
ORCID: 0000-0001-9245-0700

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Lysosome-Specific Coumarin-Based Fluorescent...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › Lysosome-Specific Coumarin-Based Fluorescent...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Lysosomes › Lysosome-Specific Coumarin-Based Fluorescent...
questionsmedicales.fr › Tumeurs › Lysosome-Specific Coumarin-Based Fluorescent...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › Lysosome-Specific Coumarin-Based Fluorescent...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › Coumarines › Lysosome-Specific Coumarin-Based Fluorescent...