α-Synuclein Drives Tau's Cytotoxic Aggregates Formation through Hydrophobic Interactions.
Tau
cell death
conformational changes
hydrophobic interactions
α-syn
Journal
ChemPlusChem
ISSN: 2192-6506
Titre abrégé: Chempluschem
Pays: Germany
ID NLM: 101580948
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
revised:
13
09
2023
received:
30
05
2023
medline:
23
10
2023
pubmed:
14
9
2023
entrez:
14
9
2023
Statut:
ppublish
Résumé
Tau and α-synuclein are proteins involved in pathologies known as tauopathies and synucleinopathies, respectively. Moreover, evidence shows that there is a crosstalk between them as is seen in the brains of individuals with sporadic neurodegenerative disorders. Based on that, we present data showing that the hydrophobic α-peptide
Identifiants
pubmed: 37708459
doi: 10.1002/cplu.202300257
doi:
Substances chimiques
alpha-Synuclein
0
tau Proteins
0
Peptides
0
Amino Acids
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e202300257Informations de copyright
© 2023 Wiley-VCH GmbH.
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