AaLaeA targets AaFla1 to mediate the production of antitumor compound in Alternaria alstroemeria.
Alternaria alstroemeria
FAD-binding domain protein
antitumor substances
global regulator AaLaeA
metabolomics
Journal
Journal of basic microbiology
ISSN: 1521-4028
Titre abrégé: J Basic Microbiol
Pays: Germany
ID NLM: 8503885
Informations de publication
Date de publication:
17 Sep 2023
17 Sep 2023
Historique:
revised:
25
08
2023
received:
08
06
2023
accepted:
05
09
2023
medline:
17
9
2023
pubmed:
17
9
2023
entrez:
17
9
2023
Statut:
aheadofprint
Résumé
Endophytic fungi are an important source of novel antitumor substances. Previously, we isolated an endophytic fungus, Alternaria alstroemeria, from the medicinal plant Artemisia artemisia, whose crude extracts strongly inhibited A549 tumor cells. We obtained a transformant, namely AaLaeA
Identifiants
pubmed: 37717245
doi: 10.1002/jobm.202300319
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : National Natural Science Foundation of China
ID : 32160667
Organisme : National Natural Science Foundation of China
ID : 31901947
Organisme : National Natural Science Foundation of China
ID : 32170019
Organisme : Qian Kehe-ZK [2021]-145
Organisme : Gui Da Ren Ji He Zi (2019) 71
Organisme : Guizhou University Incubation [2019] 19
Informations de copyright
© 2023 Wiley-VCH GmbH.
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