Dental Pulp Stem Cells and Current in vivo Approaches to Study Dental Pulp Stem Cells in Pulp Injury and Regeneration.

Dental pulp Mesenchymal

Journal

Journal of bone metabolism
ISSN: 2287-6375
Titre abrégé: J Bone Metab
Pays: Korea (South)
ID NLM: 101599927

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 15 07 2023
accepted: 20 08 2023
medline: 18 9 2023
pubmed: 18 9 2023
entrez: 18 9 2023
Statut: ppublish

Résumé

Dental pulp stem cells (DPSCs) have garnered significant interest in dental research for their unique characteristics and potential in tooth development and regeneration. While there were many studies to define their stem cell-like characteristics and osteogenic differentiation functions that are considered ideal candidates for regenerating damaged dental pulp tissue, how endogenous DPSCs respond to dental pulp injury and supply new dentin-forming cells has not been extensively investigated in vivo. Here, we review the recent progress in identity, function, and regulation of endogenous DPSCs and their clinical potential for pulp injury and regeneration. In addition, we discuss current advances in new mouse models, imaging techniques, and its practical uses and limitations in the analysis of DPSCs in pulp injury and regeneration in vivo.

Identifiants

pubmed: 37718901
pii: jbm.2023.30.3.231
doi: 10.11005/jbm.2023.30.3.231
pmc: PMC10509030
doi:

Types de publication

Journal Article

Langues

eng

Pagination

231-244

Subventions

Organisme : NIAMS NIH HHS
ID : R61AR078073
Pays : United States
Organisme : NIAMS NIH HHS
ID : 1R01AR072018
Pays : United States
Organisme : NIAMS NIH HHS
ID : T32DK060445
Pays : United States

Références

Nat Commun. 2020 Sep 23;11(1):4816
pubmed: 32968047
Adv Exp Med Biol. 2018;1107:41-52
pubmed: 30051321
J Bone Miner Res. 2003 Apr;18(4):696-704
pubmed: 12674330
Tissue Eng Regen Med. 2020 Aug;17(4):511-524
pubmed: 32592130
Expert Opin Biol Ther. 2018 Feb;18(2):187-196
pubmed: 29110535
J Dent Res. 2002 Aug;81(8):531-5
pubmed: 12147742
Development. 2020 Jan 24;147(2):
pubmed: 31980484
J Exp Biol. 1999 Dec;202(Pt 23):3285-94
pubmed: 10562511
Front Physiol. 2023 Feb 28;14:1137063
pubmed: 36926193
Dent Traumatol. 2012 Oct;28(5):336-44
pubmed: 22970995
World J Clin Cases. 2015 Jan 16;3(1):34-41
pubmed: 25610848
J Bone Miner Res. 2019 Aug;34(8):1502-1516
pubmed: 31112333
J Endod. 2017 Oct;43(10):1647-1650
pubmed: 28864220
Cytotherapy. 2018 Apr;20(4):479-498
pubmed: 29449086
J Dent Res. 2017 Mar;96(3):323-330
pubmed: 27834664
Anat Rec. 1988 Nov;222(3):289-300
pubmed: 3265042
J Dent Res. 2018 Sep;97(10):1170-1177
pubmed: 29649366
Cell Biol Int. 2008 Jul;32(7):827-34
pubmed: 18442933
Sci Rep. 2017 Jun 8;7(1):3102
pubmed: 28596530
J Conserv Dent. 2010 Jan;13(1):4-8
pubmed: 20582212
J Dent Res. 2009 Mar;88(3):229-34
pubmed: 19329455
Int J Mol Sci. 2014 Oct 15;15(10):18623-39
pubmed: 25322154
Crit Rev Oral Biol Med. 1999;10(1):4-39
pubmed: 10759425
Tissue Eng Part A. 2010 Feb;16(2):605-15
pubmed: 19737072
Int Endod J. 2008 Sep;41(9):781-90
pubmed: 18798922
Cell Stem Cell. 2012 Mar 2;10(3):259-72
pubmed: 22385654
Genesis. 2022 Sep;60(8-9):e23498
pubmed: 35980285
Int Endod J. 2000 May;33(3):173-85
pubmed: 11307433
Development. 2017 Jul 15;144(14):2560-2569
pubmed: 28576771
Vet Clin North Am Equine Pract. 1998 Aug;14(2):333-47
pubmed: 9742667
J Dent Res. 2018 Aug;97(9):1047-1054
pubmed: 29566345
Front Cell Dev Biol. 2021 Oct 29;9:758203
pubmed: 34778267
Eur Rev Med Pharmacol Sci. 2019 Feb;23(4):1626-1633
pubmed: 30840286
Stem Cells Cloning. 2014 Dec 04;7:89-99
pubmed: 25506228
Cell Stem Cell. 2014 Feb 6;14(2):160-73
pubmed: 24506883
J Dent Res. 2018 Apr;97(4):416-422
pubmed: 29185832
Stem Cell Reports. 2017 Apr 11;8(4):933-946
pubmed: 28366454
Development. 2017 Feb 1;144(3):374-384
pubmed: 28143844
Bone. 2020 Oct;139:115521
pubmed: 32629173
Methods Mol Biol. 2019;1922:91-101
pubmed: 30838567
Mech Dev. 2007 Jul;124(6):409-15
pubmed: 17449229
Stem Cells. 2015 Mar;33(3):627-38
pubmed: 25447379
J Oral Maxillofac Surg. 2009 Nov;67(11):2440-5
pubmed: 19837314
Gene Expr Patterns. 2022 Mar;43:119228
pubmed: 34915194
J Neurosci Methods. 1993 Apr;47(1-2):105-14
pubmed: 8321010
Sci Rep. 2017 Jan 09;7:39654
pubmed: 28067250
Elife. 2017 May 05;6:
pubmed: 28475038
Bone Res. 2022 Feb 18;10(1):16
pubmed: 35181672
Biomaterials. 2015 Jan;37:208-17
pubmed: 25453951
Nat Commun. 2022 Aug 16;13(1):4803
pubmed: 35974052
Proc Natl Acad Sci U S A. 2000 Dec 5;97(25):13625-30
pubmed: 11087820
Int J Mol Sci. 2021 Feb 02;22(3):
pubmed: 33540711
Cytotechnology. 2018 Oct;70(5):1479-1486
pubmed: 29938380
Exp Mol Med. 2018 Apr 13;50(4):1-14
pubmed: 29650947
J Tissue Eng Regen Med. 2015 Nov;9(11):1205-16
pubmed: 24850632
Biochem Biophys Res Commun. 2008 Apr 4;368(2):329-35
pubmed: 18230338
Nat Protoc. 2018 Oct;13(10):2247-2267
pubmed: 30218100
Cell Tissue Res. 2021 Feb;383(2):603-616
pubmed: 32803323
Front Cell Dev Biol. 2021 Jun 22;9:654559
pubmed: 34239870
J Cell Physiol. 2019 May;234(5):7186-7197
pubmed: 30362542
Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6503-8
pubmed: 21464310
Molecules. 2021 Dec 07;26(24):
pubmed: 34946506
iScience. 2021 Apr 23;24(5):102405
pubmed: 33997688
Arch Oral Biol. 2019 Feb;98:68-74
pubmed: 30465935
J Dent Res. 2006 Oct;85(10):888-93
pubmed: 16998126
J Dent Res. 2020 May;99(5):544-551
pubmed: 32156176
Arch Oral Biol. 2012 Sep;57(9):1231-40
pubmed: 22455989
Mediators Inflamm. 2015;2015:409347
pubmed: 26688616
Mol Med Rep. 2018 Jul;18(1):893-901
pubmed: 29845193
Regen Med. 2009 Sep;4(5):697-707
pubmed: 19761395
Curr Protoc Neurosci. 2001 May;Appendix 4:Appendix 4A
pubmed: 18428449
Odontology. 2011 Jan;99(1):1-7
pubmed: 21271319
World J Stem Cells. 2021 Nov 26;13(11):1647-1666
pubmed: 34909116
J Dent Res. 2011 Sep;90(9):1103-7
pubmed: 21712529
Arch Oral Biol. 2012 Mar;57(3):285-92
pubmed: 21930259
Nat Commun. 2019 Aug 9;10(1):3596
pubmed: 31399601
Dent Update. 2000 May;27(4):194-6
pubmed: 11218456
Curr Oral Health Rep. 2018;5(4):295-303
pubmed: 30524931
J Mater Sci Mater Med. 2023 Apr 1;34(4):15
pubmed: 37004591

Auteurs

Dongwook Yang (D)

Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Center for Skeletal Biology, Baylor College of Medicine, Houston, TX, USA.

Jea Giezl Niedo Solidum (JGN)

Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Department of Biochemistry & Molecular Biology, College of Medicine, University of the Philippines Manila, Manila, Philippines.

Dongsu Park (D)

Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Center for Skeletal Biology, Baylor College of Medicine, Houston, TX, USA.
Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, USA.

Classifications MeSH