The canonical HPA axis facilitates and maintains light adaptive behavior.

GAM (generalized additive models) GR (glucocorticoid receptor) light adaptation light assays stress response zebrafish

Journal

Research square
Titre abrégé: Res Sq
Pays: United States
ID NLM: 101768035

Informations de publication

Date de publication:
06 Sep 2023
Historique:
pubmed: 18 9 2023
medline: 18 9 2023
entrez: 18 9 2023
Statut: epublish

Résumé

The vertebrate stress response (SR) is mediated by the hypothalamic-pituitary-adrenal (HPA) axis and contributes to generating context appropriate physiological and behavioral changes. Although the HPA axis plays vital roles both in stressful and basal conditions, research has focused on the response under stress. To understand broader roles of the HPA axis in a changing environment, we characterized an adaptive behavior of larval zebrafish during ambient illumination changes. The glucocorticoid receptor (

Identifiants

pubmed: 37720015
doi: 10.21203/rs.3.rs-3240080/v1
pmc: PMC10503838
pii:
doi:

Types de publication

Preprint

Langues

eng

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM134732
Pays : United States

Déclaration de conflit d'intérêts

All authors declare no conflict of interest regarding this manuscript.

Auteurs

Han Lee (H)

Mayo Clinic.

Soaleha Shams (S)

Mayo Clinic.

Grace Boyum (G)

Mayo Clinic.

Emma Hall (E)

Mayo Clinic.

Fernando Miguez (F)

Iowa State University.

Karl Clark (K)

Mayo Clinic.

Classifications MeSH