Influence of structural characteristics on the binding of synthetic cannabinoids from the JWH family to the CB1 receptor: A computational study.


Journal

Journal of molecular graphics & modelling
ISSN: 1873-4243
Titre abrégé: J Mol Graph Model
Pays: United States
ID NLM: 9716237

Informations de publication

Date de publication:
Jan 2024
Historique:
received: 09 09 2022
revised: 31 07 2023
accepted: 30 08 2023
medline: 27 11 2023
pubmed: 19 9 2023
entrez: 18 9 2023
Statut: ppublish

Résumé

Synthetic cannabinoids, including some from the John W. Huffman (JWH) family, emerged on the drug scene around 2004 as "alternative marijuana," despite being considerably more potent than marijuana. Like Δ

Identifiants

pubmed: 37722351
pii: S1093-3263(23)00218-8
doi: 10.1016/j.jmgm.2023.108620
pii:
doi:

Substances chimiques

Receptor, Cannabinoid, CB1 0
Cannabinoids 0
Dronabinol 7J8897W37S
Hallucinogens 0
Naphthalenes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108620

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Krishna Chaturvedi (K)

Department of Chemistry and Biochemistry, University of Mississippi, University, Mississippi, 38677, United States.

Caroline S Anthony (CS)

Department of Chemistry and Biochemistry, University of Mississippi, University, Mississippi, 38677, United States.

Pankaj Pandey (P)

Department of BioMolecular Sciences and Research Institute of Pharmaceutical Sciences, University of Mississippi, University, Mississippi, 38677, United States; National Center for Natural Products Research, School of Pharmacy, University of Mississippi, MS 38677-1848, United States.

Robert J Doerksen (RJ)

Department of BioMolecular Sciences and Research Institute of Pharmaceutical Sciences, University of Mississippi, University, Mississippi, 38677, United States.

Murrell Godfrey (M)

Department of Chemistry and Biochemistry, University of Mississippi, University, Mississippi, 38677, United States. Electronic address: mgodfrey@olemiss.edu.

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Classifications MeSH