Endoscopic Surveillance of the Intestinal Allograft: Recommendations From the Intestinal Rehabilitation and Transplant Association Working Group.
Journal
Transplantation
ISSN: 1534-6080
Titre abrégé: Transplantation
Pays: United States
ID NLM: 0132144
Informations de publication
Date de publication:
19 Sep 2023
19 Sep 2023
Historique:
pubmed:
19
9
2023
medline:
19
9
2023
entrez:
19
9
2023
Statut:
aheadofprint
Résumé
Intestinal transplant (ITx) rejection lacks a reliable noninvasive biomarker and rejection surveillance relies on serial endoscopies and mucosal biopsies followed by histologic assessment. Endoscopic biopsies are also essential for identifying other ITx-related complications such as infectious, allergic, and inflammatory graft enteritis as well as post-transplant lymphoproliferative disease or graft versus host disease. In spite of its central role in ITx, published guidelines on endoscopy and biopsy are lacking and significant variability between centers in terms of timing and technical performance exists. Therefore, an international expert group convened and discussed several aspects related to the surveillance endoscopy after ITx with the aim to summarize and standardize its practice. This article summarizes these considerations on endoscopic ITx monitoring and highlights practices of surveillance and for-cause endoscopy, biopsy techniques, pathologic evaluation, potential risks and complications, outsourcing, and less-invasive monitoring techniques.
Identifiants
pubmed: 37723639
doi: 10.1097/TP.0000000000004785
pii: 00007890-990000000-00548
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Références
Smith JM, Weaver T, Skeans MA, et al. OPTN/SRTR 2018 Annual Data Report: intestine. Am J Transplant. 2020;20(Suppl 1):300–339.
Elsabbagh AM, Hawksworth J, Khan KM, et al. Long term survival in visceral transplant recipients in the new era: a single center experience. Am J Transplant. 2019;19:2077–2091.
Huard G, Schiano TD, Moon J, et al. Severe acute cellular rejection after intestinal transplantation is associated with poor patient graft survival. Clin Transpl. 2017;31:e12956.
Raghu VK, Beaumont JL, Everly MJ, et al. Pediatric intestinal transplantation: analysis of the intestinal transplant registry. Pediatr Transplant. 2019;23:e13580.
Varkey J, Simrén M, Jalanko H, et al. Fifteen years’ experience of intestinal and multivisceral transplantation in the Nordic countries. Scand J Gastroenterol. 2015;50:278–290.
Kara Balla A, Elsabbagh A, Khan KM, et al. Factors associated with 5- and 10-year survival after intestinal transplantation in infants and children. J Pediatr Gastroenterol Nutr. 2020;71:617–623.
Venick RS. Grant monitoring after intestinal transplantation. Curr Opin Organ Transplant. 2021;26:234–239.
Ruiz P, Bagni A, Brown R, et al. Histological criteria for the identification of acute cellular rejection in human small bowel allografts: results of the pathology workshop at the VIII International Small Bowel Transplant Symposium. Transplant Proc. 2004;36:335–337.
Crismale J, Mahmoud D, Moon J, et al. The role of endoscopy in the small intestinal transplant recipient: a review. Am J Transplant. 2021;21:1705–1712.
Bischoff SC, Singer P, Koller M, et al. Standard operating procedures for ESPEN guidelines and consensus papers. Clin Nutr. 2015;34:1043–1051.
Varkey J, Stotzer PO, Simrén M, et al. The endoscopic surveillance of the transplanted small intestine: a single center experience and a proposal for a grading score. Scand J Gastroenterol. 2018;53:134–139.
Liu L, Fischer RT, Xu L, et al. Sequential histologic changes in the healing process in small bowel allografts treated for acute cellular rejection. Transplant Proc. 2013;45:643–648.
Servais AM, Keck M, Leick M, et al. Viral enteritis in intestinal transplant recipients. Transpl Infect Dis. 2020;22:e13248.
Goldenberg V, Berbel A, Camargo JF, et al. Clostridium difficile infection in intestinal transplant recipients. Transpl Int. 2018;31:116–117.
Cheung DA, Beduschi T, Tekin A, et al. Clostridium difficile infection mimics intestinal acute cellular rejection in pediatric multivisceral transplant—a case series. Pediatr Transplant. 2020;24:e13621.
Sigurdsson L, Reyes J, Putnam PE, et al. Endoscopies in pediatric small intestinal transplant recipients: five years experience. Am J Gastroenterol. 1998;93:207–211.
Fishbein T, Novitskiy G, Mishra L, et al. NOD2-expressing bone marrow-derived cells appear to regulate epithelial innate immunity of the transplanted human small intestine. Gut. 2008;57:323–330.
Wu G, Selvaggi G, Nishida S, et al. Graft versus host disease after intestinal and multivisceral transplantation. Transplantation. 2011;91:219–224.
O’Keefe SJ, Hajj IIE, Wu T, et al. Endoscopic evaluation of small intestine transplant grafts. Transplantation. 2012;94:757–762.
Ubesie AC, Cole CR, Nathan JD, et al. Micronutrient deficiencies in pediatric and young adult intestinal transplant patients. Pediatr Transplantation. 2013;17:638–645.
Lauro A, Oltean M, Marino IR. Chronic rejection after intestinal transplant: where are we in order to avert it? Dig Dis Sci. 2018;63:551–562.
Oltean M, Hedenström P, Varkey J, et al. Endoscopic ultrasound in the monitoring of the intestinal allograft. BMJ Open Gastroenterol. 2022;9:e000792.
Dumronggittigule W, Venick RS, Dubray BJ Jr, et al. Ileostomy after intestinal transplantation: the first in depth report on techniques, complications, and outcomes. Transplantation. 2020;104:652–658.
Vianna R, Beduschi T, Tekin A, et al. 216 Cases and the evolution of multivisceral transplantation at the University of Miami over 20 years. 2015;99(Suppl 6):S119.
Watson MJ, Venick RS, Kaldas F, et al. Renal function impacts outcome after intestinal transplantation. Transplantation. 2008;86:117–122.
Moon JI, Schiano TD, Iyer KR. Routine surveillance endoscopy and biopsy after isolated intestinal transplantation-revisiting the gold standard. Clin Transplant. 2019;33:e13684.
Moon JI, Zhang H, Waldron L, et al. “Stoma or no stoma”: first report of intestinal transplantation without stoma. Am J Transplant. 2020;20:3550–3557.
Matsumoto CS, Kaufman SS, Fishbein TM. Inclusion of the colon in intestinal transplantation. Curr Opin Organ Transplant. 2011;16:312–315.
Huard G, Schiano T, Fiel MI, et al. Comparative incidence of rejection occurring in small intestinal and colonic mucosal biopsies of patients undergoing intestinal transplantation. Histopathology. 2016;69:600–606.
Nakhleh RE, Gruessner AC, Pirenne J, et al. Colon vs small bowel rejection after total bowel transplantation in a pig model. Transpl Int. 1996;9(Suppl 1):S269–S274.
Sigurdsson L, Reyes J, Todo S, et al. Anatomic variability of rejection in intestinal allografts after pediatric intestinal transplantation. J Pediatr Gastroenterol Nutr. 1998;27:403–406.
Yeh J, Ngo KD, Wozniak LJ, et al. Endoscopy following pediatric intestinal transplant. J Pediatr Gastroenterol Nutr. 2015;61:636–640.
Thakkar K, El-Serag H, Mattek N, et al. Complications of pediatric EGD: a 4-year experience in PEDS-CORI. Gastrointest Endoscop. 2007;65:213–221.
Rothbaum RJ. Complications of pediatric endoscopy. Gastrointest Endosc Clin N Am. 1996;6:445–459.
Kato T, Gaynor JJ, Nishida S, et al. Zoom endoscopic monitoring of small bowel allograft rejection. Surg Endosc. 2006;20:773–782.
Wichmann D, Nadalin S, Schweizer U, et al. Evaluating the diagnostic value of zoom endoscopic surveillance compared to routine biopsy after intestinal transplantation. Dig Liver Dis. 2022;54:385–390.
Cautero N, Gelmini R, Villa E, et al. Orthogonal polarization spectral imaging: a new tool in morphologic surveillance in intestinal transplant recipients. Transplant Proc. 2002;34:922–923.
Oltean M, Herlenius G, Dindelegan G, et al. Laser-Doppler flowmetry in the monitoring of the human intestinal allograft: a preliminary report. Transplant Proc. 2006;38:1723–1725.
Varkey J, Oltean M, Pischel AB, et al. Initial experience of video capsule endoscopy after intestinal transplantation. Transplant Direct. 2016;2:e119.