Increasing averaging beats improves the test accuracy on Holter-based late potentials in patients with myocardial infarction.

increase averaging beats of late potential late potentials myocardial infarction signal averaged electrocardiogram sudden cardiac death ventricular tachycardia

Journal

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
ISSN: 1542-474X
Titre abrégé: Ann Noninvasive Electrocardiol
Pays: United States
ID NLM: 9607443

Informations de publication

Date de publication:
11 2023
Historique:
revised: 18 08 2023
received: 24 07 2023
accepted: 04 09 2023
medline: 16 11 2023
pubmed: 19 9 2023
entrez: 19 9 2023
Statut: ppublish

Résumé

The prevalence of Holter-based late potentials (H-LPs) in cases of fatal cardiac events has increased. Although the noise level of H-LP is higher than that of conventional real-time late potential (LP) recording, a procedure to reduce the noise severity in H-LP by increasing the averaging beats has not been investigated. We enrolled 104 patients with post-myocardial infarction (MI) and 86 control participants. Among the patients, 30 reported sustained ventricular tachycardia (VT), and the remaining 74 had unrecorded VT. H-LPs were measured twice in all groups to evaluate the efficacy of increasing the averaging beats for H-LPs. Thereafter, the average of LP was calculated at 250 (default setting), 300, 400, 500, 600, 700, and 800 beats. Across all three groups (MI-VT group, MI non-VT group, and control group), the noise levels significantly decreased in consonance with the increase in averaging beats. In the MI-VT group, the H-LP positive rate considerably increased with the increase in the averaging beats from 250 to 800 both at night and daytime. In the MI-VT group, the LP parameters significantly deteriorated, which led to a positive judgment corresponding to the increment of the averaged night and day beats. The H-LP positive rates were unchanged in the MI non-VT and control groups, while the LP parameters remained consistent, despite the increased averaging beats in the MI non-VT and control groups. Increasing the calculated averaging beats in H-LPs can improve the sensitivity of predicting fatal cardiac events in patients with MI.

Sections du résumé

BACKGROUND
The prevalence of Holter-based late potentials (H-LPs) in cases of fatal cardiac events has increased. Although the noise level of H-LP is higher than that of conventional real-time late potential (LP) recording, a procedure to reduce the noise severity in H-LP by increasing the averaging beats has not been investigated.
METHODS
We enrolled 104 patients with post-myocardial infarction (MI) and 86 control participants. Among the patients, 30 reported sustained ventricular tachycardia (VT), and the remaining 74 had unrecorded VT. H-LPs were measured twice in all groups to evaluate the efficacy of increasing the averaging beats for H-LPs. Thereafter, the average of LP was calculated at 250 (default setting), 300, 400, 500, 600, 700, and 800 beats.
RESULTS
Across all three groups (MI-VT group, MI non-VT group, and control group), the noise levels significantly decreased in consonance with the increase in averaging beats. In the MI-VT group, the H-LP positive rate considerably increased with the increase in the averaging beats from 250 to 800 both at night and daytime. In the MI-VT group, the LP parameters significantly deteriorated, which led to a positive judgment corresponding to the increment of the averaged night and day beats. The H-LP positive rates were unchanged in the MI non-VT and control groups, while the LP parameters remained consistent, despite the increased averaging beats in the MI non-VT and control groups.
CONCLUSION
Increasing the calculated averaging beats in H-LPs can improve the sensitivity of predicting fatal cardiac events in patients with MI.

Identifiants

pubmed: 37724719
doi: 10.1111/anec.13089
pmc: PMC10646378
doi:

Substances chimiques

Lipopolysaccharides 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13089

Subventions

Organisme : Grants-in-Aid for Scientific Research in Japan
ID : 20K07816

Informations de copyright

© 2023 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals LLC.

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Auteurs

Kenichi Hashimoto (K)

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.

Naomi Harada (N)

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.

Motohiro Kimata (M)

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.

Yusuke Kawamura (Y)

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.
Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan.

Naoya Fujita (N)

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.

Akinori Sekizawa (A)

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.

Yosuke Ono (Y)

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.

Yasuhiro Obuchi (Y)

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.

Tadateru Takayama (T)

Department of General Medicine, Nihon University School of Medicine, Tokyo, Japan.

Yuji Kasamaki (Y)

Department of General Medicine, Kanazawa Medical College Himi Municipal Hospital, Himi, Japan.

Yuji Tanaka (Y)

Department of General Medicine, National Defense Medical College, Tokorozawa, Japan.

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