Nanofibrous PCL-Based Human Trabecular Meshwork for Aqueous Humor Outflow Studies.


Journal

ACS biomaterials science & engineering
ISSN: 2373-9878
Titre abrégé: ACS Biomater Sci Eng
Pays: United States
ID NLM: 101654670

Informations de publication

Date de publication:
13 11 2023
Historique:
medline: 14 11 2023
pubmed: 19 9 2023
entrez: 19 9 2023
Statut: ppublish

Résumé

Primary open-angle glaucoma is characterized by the progressive degeneration of the optic nerve, with the high intraocular pressure (IOP) being one of the main risk factors. The human trabecular meshwork (HTM), specifically the juxtacanalicular tissue (JCT), is responsible for placing resistance to the aqueous humor (AH) outflow and the resulting IOP control. Currently, the lack of a proper

Identifiants

pubmed: 37725561
doi: 10.1021/acsbiomaterials.3c01071
pmc: PMC10646841
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

6333-6344

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Auteurs

Maria Bikuna-Izagirre (M)

University of Navarra, TECNUN School of Engineering, Manuel Lardizabal 13, 20018 San Sebastián, Spain.
University of Navarra, Biomedical Engineering Center, Campus Universitario, 31080 Pamplona, Spain.

Javier Aldazabal (J)

University of Navarra, TECNUN School of Engineering, Manuel Lardizabal 13, 20018 San Sebastián, Spain.
University of Navarra, Biomedical Engineering Center, Campus Universitario, 31080 Pamplona, Spain.
Navarra Institute for Health Research, IdiSNA, C/Irunlarrea 3, 31008 Pamplona, Spain.

Leire Extramiana (L)

Departamento de Oftalmología Clínica, Clínica Universidad de Navarra, Avenida Pio XII, 31080 Pamplona, Spain.

Javier Moreno-Montañés (J)

Departamento de Oftalmología Clínica, Clínica Universidad de Navarra, Avenida Pio XII, 31080 Pamplona, Spain.

Elena Carnero (E)

Departamento de Oftalmología Clínica, Clínica Universidad de Navarra, Avenida Pio XII, 31080 Pamplona, Spain.

Jacobo Paredes (J)

University of Navarra, TECNUN School of Engineering, Manuel Lardizabal 13, 20018 San Sebastián, Spain.
University of Navarra, Biomedical Engineering Center, Campus Universitario, 31080 Pamplona, Spain.
Navarra Institute for Health Research, IdiSNA, C/Irunlarrea 3, 31008 Pamplona, Spain.

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Classifications MeSH