Impact of the Spatial Velocity Inlet Distribution on the Hemodynamics of the Thoracic Aorta.
CFD
Stochastic sensitivity analysis
Thoracic aorta
Uncertainty quantification
Journal
Cardiovascular engineering and technology
ISSN: 1869-4098
Titre abrégé: Cardiovasc Eng Technol
Pays: United States
ID NLM: 101531846
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
received:
21
01
2022
accepted:
01
09
2023
medline:
30
10
2023
pubmed:
20
9
2023
entrez:
19
9
2023
Statut:
ppublish
Résumé
The impact of the distribution in space of the inlet velocity in the numerical simulations of the hemodynamics in the thoracic aorta is systematically investigated. A real healthy aorta geometry, for which in-vivo measurements are available, is considered. The distribution is modeled through a truncated cone shape, which is a suitable approximation of the real one downstream of a trileaflet aortic valve during the systolic part of the cardiac cycle. The ratio between the upper and the lower base of the truncated cone and the position of the center of the upper base are selected as uncertain parameters. A stochastic approach is chosen, based on the generalized Polynomial Chaos expansion, to obtain accurate response surfaces of the quantities of interest in the parameter space. The selected parameters influence the velocity distribution in the ascending aorta. Consequently, effects on the wall shear stress are observed, confirming the need to use patient-specific inlet conditions if interested in the hemodynamics of this region. The surface base ratio is globally the most important parameter. Conversely, the impact on the velocity and wall shear stress in the aortic arch and descending aorta is almost negligible.
Identifiants
pubmed: 37726567
doi: 10.1007/s13239-023-00682-2
pii: 10.1007/s13239-023-00682-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
713-725Subventions
Organisme : Marie Curie
ID : 859836
Pays : United Kingdom
Informations de copyright
© 2023. The Author(s) under exclusive licence to Biomedical Engineering Society.
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