Sensitivity of rapid antigen tests against SARS-CoV-2 Omicron and Delta variants.
SARS-CoV-2
rapid antigen test
Journal
Journal of clinical microbiology
ISSN: 1098-660X
Titre abrégé: J Clin Microbiol
Pays: United States
ID NLM: 7505564
Informations de publication
Date de publication:
24 Oct 2023
24 Oct 2023
Historique:
medline:
20
11
2023
pubmed:
20
9
2023
entrez:
20
9
2023
Statut:
ppublish
Résumé
Rapid antigen tests (RATs) have become an invaluable tool for combating the COVID-19 pandemic. However, concerns have been raised regarding the ability of existing RATs to effectively detect emerging SARS-CoV-2 variants. We compared the performance of 10 commercially available, emergency use authorized RATs against the Delta and Omicron SARS-CoV-2 variants using both individual patient and serially diluted pooled clinical samples. The RATs exhibited lower sensitivity for Omicron samples when using PCR cycle threshold (C
Identifiants
pubmed: 37728336
doi: 10.1128/jcm.00138-23
pmc: PMC10654096
doi:
Substances chimiques
RNA
63231-63-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0013823Subventions
Organisme : NCATS NIH HHS
ID : UL1 TR002378
Pays : United States
Organisme : NIBIB NIH HHS
ID : U54 EB027690
Pays : United States
Commentaires et corrections
Type : UpdateOf
Déclaration de conflit d'intérêts
A.L.G. reports contract testing from Abbott, Cepheid, Novavax, Pfizer, Janssen, and Hologic, and research support from Gilead and Merck, outside of the described work. The other authors have declared that no conflict of interest exists.
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