COVID-19 vaccine uptake and associated factors among adolescents and youths: Findings and implications for future vaccination programmes.


Journal

PLOS global public health
ISSN: 2767-3375
Titre abrégé: PLOS Glob Public Health
Pays: United States
ID NLM: 9918283779606676

Informations de publication

Date de publication:
2023
Historique:
received: 05 07 2023
accepted: 22 08 2023
medline: 20 9 2023
pubmed: 20 9 2023
entrez: 20 9 2023
Statut: epublish

Résumé

Adolescents and youths are a key part of the population that needs to be protected against the coronavirus disease 2019 (COVID-19). This is because they are more likely to spread the virus to vulnerable individuals. In view of these concerns, this study investigated the uptake of COVID-19 vaccines and associated factors among adolescents and youths attending secondary schools in Zambia. This cross-sectional study was conducted among 1500 school-going adolescents in Lusaka from September 2022 to November 2022. Overall, 1409 participants took part giving a response rate of 94%. Only 29.2% (n = 411) of the participants were vaccinated against COVID-19 at the time of the study. Compared to their unvaccinated counterparts, vaccinated adolescents and youths scored higher for knowledge (66.2% vs 57.8%) and attitudes (76.7% vs 39.4%) regarding COVID-19 vaccines. Healthcare workers, family/friends and social media were key sources of information regarding the vaccine. Factors associated with increased vaccine uptake were positive attitudes (AOR = 33.62, 95% CI: 19.92-56.73), indicating it was stressful to follow COVID-19 preventive measures (AOR = 1.47, 95% CI: 1.09-1.99), participants in Grade 12 (AOR = 3.39, 95% CI: 1.94-5.91), Grade 11 (AOR = 2.59, 95% CI: 1.94-5.91), Grade 10 (AOR = 3.48, 95% CI: 1.98-6.11) and Grade 9 (AOR = 3.04, 95% CI: 1.74-5.32) compared to Grade 8. This study found a relatively low uptake of COVID-19 vaccines among adolescents and youths in Zambia. There is a need to provide adequate strategies to address knowledge and attitude gaps regarding COVID-19 vaccines to improve uptake and reduce future morbidity and mortality.

Identifiants

pubmed: 37729153
doi: 10.1371/journal.pgph.0002385
pii: PGPH-D-23-01286
pmc: PMC10511127
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e0002385

Informations de copyright

Copyright: © 2023 Mudenda et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

JAMA Netw Open. 2021 May 3;4(5):e2111629
pubmed: 34042990
Int J Environ Res Public Health. 2021 Mar 01;18(5):
pubmed: 33804558
Front Public Health. 2021 Oct 27;9:725980
pubmed: 34778168
Hum Vaccin Immunother. 2022 Nov 30;18(6):2090776
pubmed: 35763311
Hum Vaccin Immunother. 2021 Jun 3;17(6):1612-1621
pubmed: 33242386
Transl Behav Med. 2021 Dec 14;11(12):2194-2199
pubmed: 34529080
J Infect. 2020 Jul;81(1):107-114
pubmed: 32335167
Vaccine. 2023 Jan 16;41(3):735-743
pubmed: 36549940
Heliyon. 2022 Jan;8(1):e08806
pubmed: 35083378
MMWR Morb Mortal Wkly Rep. 2020 Mar 20;69(11):307-311
pubmed: 32191691
BMC Public Health. 2022 Jul 18;22(1):1375
pubmed: 35850675
Z Gesundh Wiss. 2021 Oct 09;:1-10
pubmed: 34660175
Ann Med. 2022 Dec;54(1):733-742
pubmed: 35238263
Nature. 2020 May;581(7806):94-99
pubmed: 32376956
PLoS One. 2022 Apr 21;17(4):e0266724
pubmed: 35446850
NPJ Vaccines. 2021 Jul 27;6(1):93
pubmed: 34315886
Hum Vaccin Immunother. 2022 Dec 31;18(1):2042135
pubmed: 35240923
PLoS One. 2022 Aug 29;17(8):e0272801
pubmed: 36037233
Vaccines (Basel). 2022 Nov 15;10(11):
pubmed: 36423029
NASN Sch Nurse. 2021 May;36(3):156-163
pubmed: 33618566
Glob Health Res Policy. 2022 Jul 19;7(1):21
pubmed: 35850783
BMC Med. 2022 May 18;20(1):196
pubmed: 35581585
Vaccines (Basel). 2022 Oct 12;10(10):
pubmed: 36298567
Cureus. 2022 Jul 25;14(7):e27230
pubmed: 35910696
Int J Infect Dis. 2021 Jan;102:455-459
pubmed: 33035675
Lancet Glob Health. 2020 Oct;8(10):e1264-e1272
pubmed: 32687792
J Prev Med Hyg. 2022 Apr 26;63(1):E1-E3
pubmed: 35647377
JMIR Public Health Surveill. 2021 Nov 17;7(11):e30642
pubmed: 34653016
Clin Infect Dis. 2021 May 4;72(9):e334-e342
pubmed: 32738143
Lancet. 2022 Feb 12;399(10325):629-655
pubmed: 35065702
Trop Med Health. 2022 Jan 5;50(1):4
pubmed: 34983692
Int J Environ Res Public Health. 2022 Jan 07;19(2):
pubmed: 35055476
Expert Rev Vaccines. 2017 Jun;16(6):625-640
pubmed: 28409537
Ann Ig. 2023 Jan-Feb;35(1):75-83
pubmed: 35532052
Lancet Digit Health. 2020 Oct;2(10):e504-e505
pubmed: 32984795
N Engl J Med. 2022 Jan 13;386(2):e2
pubmed: 34965336
PLoS One. 2022 Jan 21;17(1):e0260733
pubmed: 35061702
BMJ Open. 2021 Feb 23;11(2):e043421
pubmed: 33622946
J Gen Intern Med. 2021 Oct;36(10):3088-3095
pubmed: 34378115
Front Microbiol. 2020 Jul 14;11:1526
pubmed: 32760367
BMJ. 2020 May 18;369:m1983
pubmed: 32423901
PLOS Glob Public Health. 2022 Oct 5;2(10):e0000611
pubmed: 36962540
Pharmacoeconomics. 2016 Dec;34(12):1211-1225
pubmed: 27510721
Vaccines (Basel). 2023 Jan 28;11(2):
pubmed: 36851166
Ann Med Surg (Lond). 2022 Aug;80:104299
pubmed: 35936562
Expert Rev Vaccines. 2022 Dec;21(12):1697-1699
pubmed: 35377268
Vaccine. 2020 Jan 16;38(3):470-481
pubmed: 31767469
Lancet Glob Health. 2021 Jun;9(6):e773-e781
pubmed: 33711262
BMJ Open. 2022 Feb 25;12(2):e058416
pubmed: 35217543
Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4031-4033
pubmed: 28396427
Inform Med Unlocked. 2022;31:101000
pubmed: 35782229
Ann Work Expo Health. 2023 Jan 12;67(1):101-117
pubmed: 36111528
Lancet Reg Health West Pac. 2021 Sep;14:100223
pubmed: 34368797
BMJ. 2021 Nov 17;375:e068302
pubmed: 34789505
Vaccines (Basel). 2021 Feb 16;9(2):
pubmed: 33669441
Health Policy Technol. 2022 Jun;11(2):100620
pubmed: 35369127
Vaccines (Basel). 2022 Jul 27;10(8):
pubmed: 35893839
BMC Public Health. 2022 Oct 7;22(1):1878
pubmed: 36207702
Vaccines (Basel). 2022 Mar 11;10(3):
pubmed: 35335059
Clinicoecon Outcomes Res. 2022 Apr 28;14:293-307
pubmed: 35509962
Vaccines (Basel). 2021 Sep 30;9(10):
pubmed: 34696223
Int J Environ Res Public Health. 2021 Sep 04;18(17):
pubmed: 34501932
Br J Health Psychol. 2020 Nov;25(4):1039-1054
pubmed: 32889759
Immunity. 2021 Aug 10;54(8):1636-1651
pubmed: 34348117
Antibiotics (Basel). 2022 Jan 14;11(1):
pubmed: 35052982
J Mark Access Health Policy. 2015 Aug 12;3:
pubmed: 27123188
Elife. 2021 Jun 24;10:
pubmed: 34165077
BMC Med. 2021 Feb 10;19(1):45
pubmed: 33563270
Front Public Health. 2021 Dec 16;9:760795
pubmed: 34976922
Front Med (Lausanne). 2020 Aug 11;7:400
pubmed: 32850905
Z Gesundh Wiss. 2022;30(3):583-586
pubmed: 32837842
Vaccines (Basel). 2021 May 17;9(5):
pubmed: 34067682
Front Public Health. 2022 Mar 22;10:844310
pubmed: 35392471
Vaccines (Basel). 2022 Sep 17;10(9):
pubmed: 36146631
Vaccines (Basel). 2022 Dec 14;10(12):
pubmed: 36560551
JAMA Pediatr. 2020 Oct 1;174(10):921-922
pubmed: 32401277
Nat Commun. 2022 Jul 1;13(1):3801
pubmed: 35778396
Nat Rev Microbiol. 2019 Jan;17(1):3
pubmed: 30467331
Front Pediatr. 2021 Mar 18;9:625377
pubmed: 33816398
Hum Vaccin Immunother. 2021 Nov 2;17(11):4057-4064
pubmed: 34613864
J Public Health Manag Pract. 2021 May-Jun 01;27(3):278-284
pubmed: 33762543
Vaccine. 2021 Dec 20;39(52):7625-7632
pubmed: 34802786
Pragmat Obs Res. 2020 Oct 29;11:103-109
pubmed: 33154695
Pan Afr Med J. 2021 Dec 15;40:225
pubmed: 35145587
Patient Prefer Adherence. 2022 Aug 25;16:2321-2333
pubmed: 36046497
Science. 2020 May 29;368(6494):945-946
pubmed: 32385100
Lancet Infect Dis. 2019 Jan;19(1):56-66
pubmed: 30409683
PLOS Glob Public Health. 2022 Apr 20;2(4):e0000266
pubmed: 36962220
Lancet. 2021 Aug 7;398(10299):522-534
pubmed: 34273292
Can Commun Dis Rep. 2021 Dec 09;47(12):515-523
pubmed: 35018139
Commun Med (Lond). 2022 Sep 12;2:113
pubmed: 36101704
BMC Public Health. 2023 Jan 12;23(1):91
pubmed: 36635715
Front Pediatr. 2022 Apr 07;10:867968
pubmed: 35463893
Front Public Health. 2023 Feb 16;11:1085197
pubmed: 36875362
EClinicalMedicine. 2021 Aug;38:101035
pubmed: 34308301
Antibiotics (Basel). 2022 Apr 18;11(4):
pubmed: 35453286
Front Public Health. 2020 May 29;8:254
pubmed: 32574314
Front Pharmacol. 2020 Sep 11;11:1205
pubmed: 33071775
Procedia Vaccinol. 2011;5:127-136
pubmed: 32288915
Ther Adv Vaccines Immunother. 2022 Mar 24;10:25151355221088159
pubmed: 35355936
Vaccines (Basel). 2023 Jan 01;11(1):
pubmed: 36679949
Vaccines (Basel). 2022 Jul 26;10(8):
pubmed: 35893833
BMC Med. 2022 May 23;20(1):200
pubmed: 35606843
Int J Health Serv. 2022 Jan;52(1):9-22
pubmed: 33686893
Pediatr Infect Dis J. 2021 Apr 1;40(4):e146-e150
pubmed: 33464019
Lancet Infect Dis. 2023 Jan;23(1):5-6
pubmed: 36096145
BMC Public Health. 2021 May 29;21(1):1015
pubmed: 34051769
Cureus. 2020 Apr 4;12(4):e7541
pubmed: 32377489
J Med Internet Res. 2020 Jun 5;22(6):e20021
pubmed: 32490839
Hum Vaccin Immunother. 2021 Dec 2;17(12):4806-4815
pubmed: 34892992
Clin Microbiol Infect. 2017 May;23(5):279-280
pubmed: 27851999
Lancet. 2020 May 30;395(10238):1678-1680
pubmed: 32401713
Healthcare (Basel). 2021 Dec 13;9(12):
pubmed: 34946448
PLoS One. 2022 Jan 25;17(1):e0263081
pubmed: 35077504
Vaccines (Basel). 2021 Jun 17;9(6):
pubmed: 34204379
Arch Dis Child. 2021 Feb 16;:
pubmed: 33593743
Antibiotics (Basel). 2022 Mar 25;11(4):
pubmed: 35453198
Vaccines (Basel). 2022 Aug 08;10(8):
pubmed: 36016165
Vaccine. 2021 Apr 22;39(17):2416-2423
pubmed: 33775438
Ital J Pediatr. 2022 Dec 9;48(1):194
pubmed: 36494672
BMC Infect Dis. 2021 Apr 12;21(1):338
pubmed: 33845781

Auteurs

Steward Mudenda (S)

Department of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.

Johanna C Meyer (JC)

Department of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
South African Vaccination and Immunisation Centre, Sefako Makgatho Health Sciences University, Pretoria, South Africa.

Joseph O Fadare (JO)

Department of Pharmacology and Therapeutics, Ekiti State University, Ado Ekiti, Nigeria.
Department of Medicine, Ekiti State University Teaching Hospital, Ado Ekiti, Nigeria.

Olayinka O Ogunleye (OO)

Department of Pharmacology, Therapeutics and Toxicology, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria.
Department of Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.

Zikria Saleem (Z)

Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan.

Scott K Matafwali (SK)

Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene &Tropical Medicine, London, United Kingdom.

Victor Daka (V)

Department of Public Health, Michael Chilufya Sata School of Medicine, Copperbelt University, Ndola, Zambia.

Billy Chabalenge (B)

Department of Medicines Control, Zambia Medicines Regulatory Authority, Lusaka, Zambia.

Jacob Chama (J)

Department of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.

Moses Mukosha (M)

Department of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.
HIV and Women's Health Research Group, University Teaching Hospital, Lusaka, Zambia.

Phumzile Skosana (P)

Department of Clinical Pharmacy, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.

Bwalya A Witika (BA)

Department of Pharmaceutical Sciences, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.

Aubrey C Kalungia (AC)

Department of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.

Audrey Hamachila (A)

Department of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.

Webrod Mufwambi (W)

Department of Pharmacy, School of Health Sciences, University of Zambia, Lusaka, Zambia.

Brian Godman (B)

Department of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.

Classifications MeSH