A Review on the Antimutagenic and Anticancer Effects of Cysteamine.


Journal

Advances in pharmacological and pharmaceutical sciences
ISSN: 2633-4690
Titre abrégé: Adv Pharmacol Pharm Sci
Pays: England
ID NLM: 101762941

Informations de publication

Date de publication:
2023
Historique:
received: 22 12 2022
revised: 03 08 2023
accepted: 17 08 2023
medline: 21 9 2023
pubmed: 21 9 2023
entrez: 21 9 2023
Statut: epublish

Résumé

Cancer is one of the leading causes of death worldwide. First-line treatments usually include surgery, radiotherapy, and/or systemic therapy. These methods can be associated with serious adverse events and can be toxic to healthy cells. Despite the new advances in cancer therapies, there is still a continuous need for safe and effective therapeutic agents. Cysteamine is an aminothiol endogenously synthetized by human cells during the degradation of coenzyme-A. It has been safely used in humans for the treatment of several pathologies including cystinosis and neurodegenerative diseases. Cysteamine has been shown to be a potent antimutagenic, anticarcinogenic, and antimelanoma in various

Identifiants

pubmed: 37731680
doi: 10.1155/2023/2419444
pmc: PMC10508993
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

2419444

Informations de copyright

Copyright © 2023 Chun-Man Lee.

Déclaration de conflit d'intérêts

The author declares that there are no conflicts of interest.

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Auteurs

Chun-Man Lee (CM)

Frimley Health NHS Foundation Trust, Portsmouth Road, Frimley, Camberley GU16 7UJ, UK.

Classifications MeSH