Novel technique of detecting inflammatory and osseous changes in the glenohumeral joint associated with patient age and weight using FDG- and NaF-PET imaging.
BMI
FDG
Glenohumeral joint
NaF
PET
aging
arthritis
limb laterality
Journal
American journal of nuclear medicine and molecular imaging
ISSN: 2160-8407
Titre abrégé: Am J Nucl Med Mol Imaging
Pays: United States
ID NLM: 101564121
Informations de publication
Date de publication:
2023
2023
Historique:
received:
27
05
2023
accepted:
30
07
2023
medline:
22
9
2023
pubmed:
22
9
2023
entrez:
22
9
2023
Statut:
epublish
Résumé
The glenohumeral (GH) joint is a classic ball-and-socket joint of the shoulder subject to various pathologies including osteoarthritis (OA). Degenerative changes of the OA evident on traditional imaging are proceeded by molecular changes, which if detected early could enhance disease prevention and treatment. In this study, we use FDG and NaF-PET/CT scans of 41 females (mean age of 43.9 ± 14.2 years) and 45 males (mean age of 44.5 ± 13.8 years) were analyzed with a semi-quantitative technique based on predefined region of interest. There was greater FDG uptake in the left side of the GH joint compared to the right in both females (left: 0.79 ± 0.17, right: 0.71 ± 0.2; Our study demonstrates the varying effect of limb laterality and BMI on FDG and NaF uptake at the GH joint. Adoption of molecular imaging will require future studies that correlate tracer uptake with relevant medical and illness history as well as degenerative change evident on traditional imaging.
Types de publication
Journal Article
Langues
eng
Pagination
136-146Informations de copyright
AJNMMI Copyright © 2023.
Déclaration de conflit d'intérêts
None.
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