Impact of the COVID-19 Pandemic on Iron Overload Assessment by MRI in Patients with Hemoglobinopathies: The E-MIOT Network Experience.
COVID-19
iron overload
magnetic resonance imaging
Journal
Tomography (Ann Arbor, Mich.)
ISSN: 2379-139X
Titre abrégé: Tomography
Pays: Switzerland
ID NLM: 101671170
Informations de publication
Date de publication:
11 09 2023
11 09 2023
Historique:
received:
27
07
2023
revised:
04
09
2023
accepted:
07
09
2023
medline:
25
9
2023
pubmed:
22
9
2023
entrez:
22
9
2023
Statut:
epublish
Résumé
The E-MIOT (Extension-Myocardial Iron Overload in Thalassemia) project is an Italian Network assuring high-quality quantification of tissue iron overload by magnetic resonance imaging (MRI). We evaluated the impact of the COVID-19 pandemic on E-MIOT services. The activity of the E-MIOT Network MRI centers in the year 2020 was compared with that of 2019. A survey evaluated whether the availability of MRI slots for patients with hemoglobinopathies was reduced and why. The total number of MRI scans was 656 in 2019 and 350 in 2020, with an overall decline of 46.4% (first MRI: 71.7%, follow-up MRI: 36.9%), a marked decline (86.9%) in the period March-June 2020, and a reduction in the gap between the two years in the period July-September. A new drop (41.4%) was recorded in the period October-December for two centers, due to the general reduction in the total amount of MRIs/day for sanitization procedures. In some centers, patients refused MRI scans for fear of getting COVID. Drops in the MRI services >80% were found for patients coming from a region without an active MRI site. The COVID-19 pandemic had a strong negative impact on MRI multi-organ iron quantification, with a worsening in the management of patients with hemoglobinopathies.
Sections du résumé
BACKGROUND
The E-MIOT (Extension-Myocardial Iron Overload in Thalassemia) project is an Italian Network assuring high-quality quantification of tissue iron overload by magnetic resonance imaging (MRI). We evaluated the impact of the COVID-19 pandemic on E-MIOT services.
METHODS
The activity of the E-MIOT Network MRI centers in the year 2020 was compared with that of 2019. A survey evaluated whether the availability of MRI slots for patients with hemoglobinopathies was reduced and why.
RESULTS
The total number of MRI scans was 656 in 2019 and 350 in 2020, with an overall decline of 46.4% (first MRI: 71.7%, follow-up MRI: 36.9%), a marked decline (86.9%) in the period March-June 2020, and a reduction in the gap between the two years in the period July-September. A new drop (41.4%) was recorded in the period October-December for two centers, due to the general reduction in the total amount of MRIs/day for sanitization procedures. In some centers, patients refused MRI scans for fear of getting COVID. Drops in the MRI services >80% were found for patients coming from a region without an active MRI site.
CONCLUSIONS
The COVID-19 pandemic had a strong negative impact on MRI multi-organ iron quantification, with a worsening in the management of patients with hemoglobinopathies.
Identifiants
pubmed: 37736989
pii: tomography9050136
doi: 10.3390/tomography9050136
pmc: PMC10514849
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1711-1722Références
N Engl J Med. 2000 Jun 22;342(25):1855-65
pubmed: 10861320
Int J Mol Sci. 2017 Dec 20;18(12):
pubmed: 29261151
Magn Reson Imaging. 2009 Feb;27(2):188-97
pubmed: 18667287
N Engl J Med. 2005 Sep 15;353(11):1135-46
pubmed: 16162884
Diabetes Care. 2020 Nov;43(11):2830-2839
pubmed: 32887708
Abdom Imaging. 2015 Oct;40(8):3129-36
pubmed: 26288986
Eur Heart J. 2001 Dec;22(23):2171-9
pubmed: 11913479
Graefes Arch Clin Exp Ophthalmol. 2020 Dec;258(12):2655-2660
pubmed: 32960319
Blood. 2010 Jun 3;115(22):4331-6
pubmed: 20233970
Br J Haematol. 2017 Jun;177(5):703-716
pubmed: 28295188
Lancet. 2020 Apr 11;395(10231):1225-1228
pubmed: 32178769
Mediterr J Hematol Infect Dis. 2009 Jul 27;1(1):e2009003
pubmed: 21415985
Br J Haematol. 2018 Dec;183(5):783-795
pubmed: 30334574
BMJ. 1997 Jun 7;314(7095):1675-8
pubmed: 9193293
Magn Reson Med. 2010 Jul;64(1):211-9
pubmed: 20572148
Am J Hematol. 2012 Feb;87(2):167-71
pubmed: 22213195
Magn Reson Med. 2011 Mar;65(3):764-9
pubmed: 21337408
Ann N Y Acad Sci. 2005;1054:386-95
pubmed: 16339687
N Engl J Med. 2000 Aug 3;343(5):327-31
pubmed: 10922422
Eur Heart J. 2022 Jul 7;43(26):2482-2492
pubmed: 34907420
Am J Hematol. 2012 Feb;87(2):155-60
pubmed: 22120775
Int J Cardiol. 2014 Dec 20;177(3):1012-9
pubmed: 25449516
Blood. 2002 Jul 1;100(1):17-21
pubmed: 12070002
J Magn Reson Imaging. 2006 May;23(5):662-8
pubmed: 16568436
N Engl J Med. 1997 Sep 11;337(11):762-9
pubmed: 9287233
Genet Med. 2017 Jun;19(6):609-619
pubmed: 27811859
Blood. 2005 Aug 15;106(4):1460-5
pubmed: 15860670
Eur Radiol. 2019 May;29(5):2246-2252
pubmed: 30338366
J Pediatr. 2001 Dec;139(6):785-9
pubmed: 11743502
Circulation. 2013 Jul 16;128(3):281-308
pubmed: 23775258
J Magn Reson Imaging. 2011 Feb;33(2):348-55
pubmed: 21274976
Am J Hematol. 2020 Aug;95(8):E198-E199
pubmed: 32311145
J Cardiovasc Magn Reson. 2008 Sep 25;10:42
pubmed: 18817553
J Magn Reson Imaging. 2009 Jul;30(1):62-8
pubmed: 19557847
Blood Adv. 2021 Jan 12;5(1):207-215
pubmed: 33570644
NMR Biomed. 2007 Oct;20(6):578-90
pubmed: 17205488
Transfus Apher Sci. 2021 Jun;60(3):103080
pubmed: 33608217
Circulation. 2002 Jan 29;105(4):539-42
pubmed: 11815441
Br J Haematol. 2013 Jun;161(6):888-91
pubmed: 23496418
Ann N Y Acad Sci. 2010 Aug;1202:123-8
pubmed: 20712782
Front Public Health. 2020 Dec 08;8:588852
pubmed: 33364225
J Blood Med. 2019 Sep 17;10:323-334
pubmed: 31572038
Adv Hematol. 2010;2010:358283
pubmed: 20467559
Open Heart. 2020 Aug;7(2):
pubmed: 32855212
Eur Heart J Cardiovasc Imaging. 2015 Mar;16(3):325-34
pubmed: 25246505
Br J Haematol. 2020 Aug;190(3):e137-e140
pubmed: 32484906
Ophthalmol Ther. 2020 Jun;9(2):231-234
pubmed: 32333375