Egress of resident memory T cells from tissue with neoadjuvant immunotherapy: Implications for systemic anti-tumor immunity.


Journal

Oral oncology
ISSN: 1879-0593
Titre abrégé: Oral Oncol
Pays: England
ID NLM: 9709118

Informations de publication

Date de publication:
11 2023
Historique:
received: 04 06 2023
revised: 11 09 2023
accepted: 16 09 2023
pmc-release: 01 11 2024
medline: 23 10 2023
pubmed: 23 9 2023
entrez: 22 9 2023
Statut: ppublish

Résumé

Resident memory T (T The presence of T Reversing tumor sequestration of tumor-specific T cells prior to surgical removal or radiation of tumor may increase systemic antitumor immunity. This finding may underlie the improved recurrence free survival observed with neoadjuvant immunotherapy in clinical trials.

Identifiants

pubmed: 37738775
pii: S1368-8375(23)00266-X
doi: 10.1016/j.oraloncology.2023.106570
pmc: PMC10591905
mid: NIHMS1934288
pii:
doi:

Substances chimiques

Transforming Growth Factor beta 0

Types de publication

Journal Article Review Research Support, N.I.H., Intramural Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

106570

Subventions

Organisme : Intramural NIH HHS
ID : ZIA BC012131
Pays : United States

Informations de copyright

Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Magdalena A Rainey (MA)

Head and Neck Section, Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

Clint T Allen (CT)

National Institutes of Health, 9000 Rockville Pike, Building 10, Room 7N240C, Bethesda, MD 20892, USA. Electronic address: clint.allen@nih.gov.

Marco Craveiro (M)

Head and Neck Section, Surgical Oncology Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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