The timing of confidence computations in human prefrontal cortex.
Confidence
DLPFC
Metacognition
Perceptual decision making
TMS
Journal
Cortex; a journal devoted to the study of the nervous system and behavior
ISSN: 1973-8102
Titre abrégé: Cortex
Pays: Italy
ID NLM: 0100725
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
received:
21
03
2023
revised:
11
07
2023
accepted:
17
08
2023
pmc-release:
01
11
2024
pubmed:
24
9
2023
medline:
24
9
2023
entrez:
23
9
2023
Statut:
ppublish
Résumé
Knowing when confidence computations take place is critical for building a mechanistic understanding of the neural and computational bases of metacognition. Yet, even though a substantial amount of research has focused on revealing the neural correlates and computations underlying human confidence judgments, very little is known about the timing of confidence computations. To understand when confidence is computed, we delivered single pulses of transcranial magnetic stimulation (TMS) at different times after stimulus presentation while subjects judged the orientation of a briefly presented visual stimulus and provided a confidence rating. TMS was delivered to either the right dorsolateral prefrontal cortex (DLPFC) in the experimental group or to vertex in the control group. We found that TMS to right DLPFC, but not to vertex, led to increased confidence in the absence of changes to accuracy or metacognitive efficiency. Critically, equivalent levels of confidence increase occurred for TMS delivered between 200 and 500 msec after stimulus presentation. These results suggest that confidence computations occur during a broad window that begins before the perceptual decision has been fully made and thus provide important constraints for theories of confidence generation.
Identifiants
pubmed: 37741132
pii: S0010-9452(23)00207-1
doi: 10.1016/j.cortex.2023.08.009
pmc: PMC10591908
mid: NIHMS1930403
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
167-175Subventions
Organisme : NIMH NIH HHS
ID : R01 MH119189
Pays : United States
Commentaires et corrections
Type : UpdateOf
Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
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