Protecting axons in grandchildren.

Animals Reproduction Caenorhabditis elegans / genetics Axons
C. elegans axon degeneration intergenerational neuroprotection non-Mendelian sphingolipid

Journal

Trends in genetics : TIG
ISSN: 0168-9525
Titre abrégé: Trends Genet
Pays: England
ID NLM: 8507085

Informations de publication

Date de publication:
12 2023
Historique:
received: 11 09 2023
accepted: 13 09 2023
medline: 16 11 2023
pubmed: 25 9 2023
entrez: 24 9 2023
Statut: ppublish

Résumé

Prenatal exposure to environmental agents can influence the fitness of not only the fetus, but also subsequent generations. In a recent study, Wang et al. demonstrated that feeding ursolic acid (UA), a plant-derived compound, to Caenorhabditis elegans mothers during their reproductive period prevented neurodegeneration in not only their offspring, but also the F2 progeny.

Identifiants

DOI: 10.1016/j.tig.2023.09.005 PMID: 37743186
pubmed: 37743186
pii: S0168-9525(23)00222-6
doi: 10.1016/j.tig.2023.09.005
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

892-894

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The author declares no competing interests.

Auteurs

Surojit Sural (S)

Department of Biological Sciences, Howard Hughes Medical Institute, Columbia University, New York, NY, USA. Electronic address: ss5950@columbia.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Protecting axons in grandchildren.
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Protecting axons in grandchildren.
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Helminthes › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Caenorhabditis › Caenorhabditis elegans › Protecting axons in grandchildren.
questionsmedicales.fr › Cellules › Neurones › Neurofibres › Axones › Protecting axons in grandchildren.