Catalytic performance and antibacterial behaviour with molecular docking analysis of silver and polyacrylic acid doped graphene quantum dots.


Journal

RSC advances
ISSN: 2046-2069
Titre abrégé: RSC Adv
Pays: England
ID NLM: 101581657

Informations de publication

Date de publication:
18 Sep 2023
Historique:
received: 14 07 2023
accepted: 16 09 2023
medline: 25 9 2023
pubmed: 25 9 2023
entrez: 25 9 2023
Statut: epublish

Résumé

In this research, a fixed concentration (3 wt%) of Ag/PAA and PAA/Ag doped graphene quantum dots (GQDs) were synthesized using the co-precipitation technique. A variety of characterization techniques were employed to synthesize samples to investigate their optical, morphological, structural, and compositional analyses, antimicrobial efficacy, and dye degradation potential with molecular docking analysis. GQDs have high solubility, narrow band gaps, and are suitable for electron acceptors and donors but show less adsorption and catalytic behavior. Incorporating polyacrylic acid (PAA) into GQDs increases the catalytic and antibacterial activities due to the carboxylic group (-COOH). Furthermore, introducing silver (Ag) increased the degradation of dye and microbes as it had a high surface-to-volume ratio. In addition, molecular docking studies were used to decipher the mechanism underlying the bactericidal action of silver and polyacrylic acid-doped graphene quantum dots and revealed inhibition of β-lactamase and DNA gyrase.

Identifiants

pubmed: 37746345
doi: 10.1039/d3ra04741e
pii: d3ra04741e
pmc: PMC10517100
doi:

Types de publication

Journal Article

Langues

eng

Pagination

28008-28020

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

The authors declare “no conflict of interest”.

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Auteurs

Tahreem Aziz (T)

Department of Chemistry, Government College University, Faisalabad Pakpattan Road Sahiwal Punjab 57000 Pakistan.

Muhammad Imran (M)

Department of Chemistry, Government College University, Faisalabad Pakpattan Road Sahiwal Punjab 57000 Pakistan.

Ali Haider (A)

Department of Clinical Sciences, Faculty of Veterinary and Animal Sciences, Muhammad Nawaz Shareef University of Agriculture Multan 66000 Punjab Pakistan.

Anum Shahzadi (A)

Faculty of Pharmacy, The University of Lahore Lahore 54000 Pakistan.

Muhammad Zain Ul Abidin (MZ)

Solar Cell Applications Research Lab, Department of Physics, Government College University Lahore Lahore 54000 Punjab Pakistan dr.muhammadikram@gcu.edu.pk.

Anwar Ul-Hamid (A)

Core Research Facilities, King Fahd University of Petroleum & Minerals Dhahran 31261 Saudi Arabia.

Walid Nabgan (W)

Departament d'Enginyeria Química, Universitat Rovira i Virgili Av Països Catalans 26 43007 Tarragona Spain walid.nabgan@urv.cat.

Mohammed M Algaradah (MM)

Chemistry Department, King Khalid Military Academy Riyadh 11495 Saudi Arabia.

Ahmed M Fouda (AM)

Chemistry Department, Faculty of Science, King Khalid University Abha 61413 Saudi Arabia.

Muhammad Ikram (M)

Solar Cell Applications Research Lab, Department of Physics, Government College University Lahore Lahore 54000 Punjab Pakistan dr.muhammadikram@gcu.edu.pk.

Classifications MeSH