Non-Invasive Biochemical Testing of ACTH-dependent Cushing's Disease: Do We Still Need Petrosal Sinus Sampling?

ACTH-dependent Cushing BIPSS non-invasive testing

Journal

Archives of medical research
ISSN: 1873-5487
Titre abrégé: Arch Med Res
Pays: United States
ID NLM: 9312706

Informations de publication

Date de publication:
23 Sep 2023
Historique:
received: 31 05 2023
revised: 14 08 2023
accepted: 21 08 2023
medline: 26 9 2023
pubmed: 26 9 2023
entrez: 25 9 2023
Statut: aheadofprint

Résumé

Differentiating between a pituitary from an ectopic source of ACTH could be a real one of the major challenges of clinical endocrinology. The Bilateral inferior petrosal sinus sampling (BIPSS) is considered the gold standard for identifying the source of ACTH; however, is not available worldwide. After the SARS-CoV-2 pandemic, algorithms that include biochemical and imaging tests have gained importance as an alternative to BIPSS. This review summarizes the drawbacks in the differential diagnosis of ACTH-dependent Cushing; the evolution of diagnostic tests, and the evidence that exists on their performance. As well as a comparison between the advantages and disadvantages of invasive and non-invasive tests.

Identifiants

pubmed: 37749028
pii: S0188-4409(23)00120-0
doi: 10.1016/j.arcmed.2023.102882
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102882

Informations de copyright

Copyright © 2023 Instituto Mexicano del Seguro Social (IMSS). Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest The authors have no competing interests to declare that are relevant to the content of this article.

Auteurs

Etual Espinosa-Cardenas (E)

Endocrinology Department, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico. Electronic address: espinosaetual@gmail.com.

Manuel Garcia-Saenz (M)

Endocrinology Department, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

Ana Laura Espinosa de Los Monteros-Sanchez (ALE)

Endocrine Research Unit, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social.

Ernesto Sosa-Eroza (E)

Endocrinology Department, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

Classifications MeSH